Decreased humoral immunity to mumps in young adults immunized with MMR vaccine in childhood

In the past decade, multiple mumps outbreaks have occurred in the United States, primarily in close-contact, high-density settings such as colleges, with a high attack rate among young adults, many of whom had the recommended 2 doses of mumps-measles-rubella (MMR) vaccine. Waning humoral immunity an...

Full description

Saved in:

Bibliographic Details
Published in:	Proceedings of the National Academy of Sciences - PNAS 2019-09, Vol.116 (38), p.19071-19076
Main Authors:	Rasheed, Mohammed Ata Ur, Hickman, Carole J., McGrew, Marcia, Sowers, Sun Bae, Mercader, Sara, Hopkins, Amy, Grimes, Vickie, Yu, Tianwei, Wrammert, Jens, Mulligan, Mark J., Bellini, William J., Rota, Paul A., Orenstein, Walter A., Ahmed, Rafi, Edupuganti, Srilatha
Format:	Article
Language:	English
Subjects:	Adolescent Adult Adults Antibodies Antibodies, Neutralizing - blood Antibodies, Neutralizing - immunology Antibodies, Viral - blood Antibodies, Viral - immunology Avidity Biological Sciences Child Child, Preschool Children Enzyme-linked immunosorbent assay Female Genotypes Humans Humoral immunity Immune response (cell-mediated) Immunity Immunity, Humoral - drug effects Immunity, Humoral - immunology Immunization Immunoglobulin G Immunoglobulin G - blood Immunoglobulin G - immunology Immunological memory Immunology and Inflammation Infant Lymphocytes Lymphocytes B Lymphocytes T Male Measles Measles-Mumps-Rubella Vaccine - administration & dosage Measles-Mumps-Rubella Vaccine - pharmacology Memory cells Mumps Mumps - immunology Mumps - prevention & control Mumps - virology Mumps virus - immunology Neutralization Outbreaks Rubella Serology Vaccines Young Adult Young adults
Citations:	Items that this one cites Items that cite this one
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!