Effects of n-3 fatty acids, EPA v. DHA, on depressive symptoms, quality of life, memory and executive function in older adults with mild cognitive impairment: a 6-month randomised controlled trial

Depressive symptoms may increase the risk of progressing from mild cognitive impairment (MCI) to dementia. Consumption of n-3 PUFA may alleviate both cognitive decline and depression. The aim of the present study was to investigate the benefits of supplementing a diet with n-3 PUFA, DHA and EPA, for...

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Bibliographic Details
Published in:British journal of nutrition 2012-06, Vol.107 (11), p.1682-1693
Main Authors: Sinn, Natalie, Milte, Catherine M., Street, Steven J., Buckley, Jonathan D., Coates, Alison M., Petkov, John, Howe, Peter R. C.
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Australia
Biological and medical sciences
Clinical trials
cognition
Cognition Disorders - blood
Cognition Disorders - diet therapy
Cognition Disorders - physiopathology
Cognition Disorders - psychology
Cognitive ability
dementia
Dementia disorders
Depression - blood
Depression - diet therapy
Depression - physiopathology
Depression - psychology
diet
Dietary supplements
Dietary Supplements - analysis
Docosahexaenoic Acids - analysis
Docosahexaenoic Acids - metabolism
Docosahexaenoic Acids - therapeutic use
Eicosapentaenoic Acid - analysis
Eicosapentaenoic Acid - metabolism
Eicosapentaenoic Acid - therapeutic use
elderly
erythrocytes
Erythrocytes - metabolism
Executive Function
fatty acid composition
Fatty acids
Fatty Acids, Omega-3 - analysis
Fatty Acids, Omega-3 - metabolism
Fatty Acids, Omega-3 - therapeutic use
Feeding. Feeding behavior
Female
Fish Oils - chemistry
Fish Oils - metabolism
Fish Oils - therapeutic use
Fundamental and applied biological sciences. Psychology
Human and Clinical Nutrition
Humans
linoleic acid
Male
Memory
Memory Disorders - etiology
Memory Disorders - prevention & control
Mental depression
mental health
Older people
omega-3 fatty acids
omega-6 fatty acids
Patient Dropouts
people
polyunsaturated fatty acids
Psychiatric Status Rating Scales
Quality of Life
questionnaires
randomized clinical trials
risk
Severity of Illness Index
Speech Disorders - etiology
Speech Disorders - prevention & control
Vertebrates: anatomy and physiology, studies on body, several organs or systems
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