P-440: Ethnic differences in central and augmentation index; do they account for differing susceptibility to left ventricular hypertrophy

People of Black African descent have a greater susceptibility to vascular target organ damage not wholly accounted for by blood pressure. We hypothesized that ethnic differences in central pressures, and/or augmentation index, may additionally account for the greater risk of left ventricular hypertr...

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Bibliographic Details
Published in:American journal of hypertension 2004-05, Vol.17 (S1), p.195A-195A
Main Authors: Chaturvedi, Nishi, Rajkumar, Chakravarthi, Strain, William D., Nihoyannopoulos, Petros, Shore, Angela C., Bulpitt, Christopher J.
Format: Article
Language:English
Subjects:
Augmentation Index
Central Pressure
Left Ventricular Hypertrophy
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Summary:People of Black African descent have a greater susceptibility to vascular target organ damage not wholly accounted for by blood pressure. We hypothesized that ethnic differences in central pressures, and/or augmentation index, may additionally account for the greater risk of left ventricular hypertrophy (LVH) in this population. Central pressure and augmentation index was derived using radial tonometry, using the Sphygmocor® device, and inter ventricular septal thickness (IVST) as a proxy for LVH was measured by echocardiography, in an unselected population sample of 101 Europeans and 99 African Caribbeans aged 40-64 years in London, UK. Mean age and sex adjusted (± SEM) results were as follows in Europeans and African Caribbeans respectively, resting brachial mean arterial pressure (MAP), 95 ± 1.1 and 102 ± 1.1 mmHg, p
ISSN:0895-7061
1941-7225
1879-1905
DOI:10.1016/j.amjhyper.2004.03.514