P-53: Characteristics of nocturnal dipping and nondipping 24-hour ambulatory blood pressure pattern and its associated mortality risk at a tertiary hypertension center

• Published in: American journal of hypertension 2005-05, Vol.18 (S4), p.27A-27A
• Main Authors: Choi, Kenneth L., Bhatt, Paras, Elliott, William J.
• Format: Article
• Language: English
• Subjects: Ambulatory Blood Pressure Monitor; Mortality; Nocturnal Nondipping Blood Pressure
• ISSN: 0895-7061; 1941-7225; 1879-1905
• DOI: 10.1016/j.amjhyper.2005.03.071

Several prospective studies have shown that a nocturnal nondipping 24 hour ambulatory blood pressure pattern is associated with increased risk for mortality and cardiovascular events. We analyzed 553 patients who had a 24 hour ambulatory blood pressure monitor (ABPM) performed at our hypertension center from 1990 through 2004, and obtained mortality information from the Social Security Death Index through 01 November 2004. A normal nocturnal dipping pattern was defined by a greater than 10% decrease in average nocturnal systolic blood pressure (BP) compared to average daytime systolic BP. All patients who did not meet this criteria were classified as having a nocturnal nondipping pattern. The 332 (60.0%) patients with a nocturnal nondipping pattern were more likely to be female (52.7 vs 43.4%; P = 0.0003), had a higher average BP (136.3±15.2/81.8±10.5 vs 130.9±13.4/79.4±8.5 mm Hg, mean±standard deviation; P < 0.001/0.003) and tended to be older (57.2 vs 54.9 years; P = 0.077) compared to the 221 (40.0%) patients with a normal nocturnal dipping pattern. The average nighttime systolic and diastolic BPs were higher in patients with a nondipping pattern compared to patients with a dipping pattern (134.3±16.1/78.9±11.1 vs 115.4±13.7/68.5±7.9 mmHg; p