P-211: Parallel morning and evening surge in stroke onset, blood pressure and physical activity

Background and Purpose: A circadian variation with a morning peak upon waking and arising is known to occur in both blood pressure (BP) and cardiovascular event onset. A second peak in BP has been described to occur after an afternoon sleep (siesta). This study was designed to test the hypothesis th...

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Bibliographic Details
Published in:American journal of hypertension 2002-04, Vol.15 (S3), p.106A-106A
Main Authors: Stergiou, George S., Vemmos, Kostas N., Pliarchopoulou, Kyriaki M., Synetos, Andreas G., Roussias, Leonidas G., Mountokalakis, Theodore D.
Format: Article
Language:English
Subjects:
Ambulatory Monitoring
Circadian Rhythm
Stroke Onset
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Summary:Background and Purpose: A circadian variation with a morning peak upon waking and arising is known to occur in both blood pressure (BP) and cardiovascular event onset. A second peak in BP has been described to occur after an afternoon sleep (siesta). This study was designed to test the hypothesis that the two-peak diurnal variation of BP is dependent on physical activity and occurs in parallel with the diurnal variation of stroke onset. Methods: The diurnal variation of stroke onset was compared to the diurnal variation of BP, pulse rate (PR) and physical activity in three independent groups of Greek hypertensives aged 50-80 years (633 stroke patients; 379 subjects with 24-hour ambulatory BP monitoring; 50 subjects with 24-hour physical activity monitoring using wrist devices). Results: The diurnal variation of stroke onset, BP and PR all showed one morning and one evening peak with a decline in the afternoon and at night and occurred in parallel with the diurnal variation in physical activity (p
ISSN:0895-7061
1941-7225
1879-1905
DOI:10.1016/S0895-7061(02)02562-1