OR-30: Stress induced impaired pressure natriuresis is associated with an extended period of elevated blood pressure in black youths

Background: Blacks have a greater prevalence of hypertension and associated target organ damage than Whites. Salt and stress are two risk factors that have been associated with these differences. Hypothesis: Stress induced impaired sodium regulation results in an extended period of elevated blood pr...

Full description

Saved in:
Bibliographic Details
Published in:American journal of hypertension 2002-04, Vol.15 (S3), p.14A-14A
Main Authors: Harshfield, Gregory A., Wilson, Martha E., Mackey, Lynne, Gillis, Delores, Treiber, Frank A., Hanevold, Coral D., Kapuku, Gaston K.
Format: Article
Language:English
Subjects:
Blood Presure
Race Differences
Sodium Regulation
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by
cites
container_end_page 14A
container_issue S3
container_start_page 14A
container_title American journal of hypertension
container_volume 15
creator Harshfield, Gregory A.
Wilson, Martha E.
Mackey, Lynne
Gillis, Delores
Treiber, Frank A.
Hanevold, Coral D.
Kapuku, Gaston K.
description Background: Blacks have a greater prevalence of hypertension and associated target organ damage than Whites. Salt and stress are two risk factors that have been associated with these differences. Hypothesis: Stress induced impaired sodium regulation results in an extended period of elevated blood pressure in Blacks. The resulting increased cardiovascular load contributes to the premature development of hypertension in Blacks. Methods: Black youths (n=121; aged 15-18 years) were brought into similar levels of sodium balance. Sodium excretion (UNaV) and systolic blood pressure (SBP) were measured during a one hour stress period which was preceded and followed by two hour rest periods. The subjects were divided into two groups based on the direction of change in UNaV during the stress period: excrete (n = 82); and retain (n = 39). Results: The time by group interactions were significant for both variables (P
doi_str_mv 10.1016/S0895-7061(02)02310-5
format article
fullrecord <record><control><sourceid>proquest_istex</sourceid><recordid>TN_cdi_proquest_journals_1026589124</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2712863641</sourcerecordid><originalsourceid>FETCH-LOGICAL-i664-416be331a44c81995e15579cce6f97233b53e243f52640b96484cb7fe191726a3</originalsourceid><addsrcrecordid>eNpNjUtLAzEAhIMoWKs_QQh40cNq3rvxJkWtWim4PYiXkN3N0vSxqUlW27s_3K0V8TTD8M0MAKcYXWKExVWOMsmTFAl8jsgFIhSjhO-BHpYMJykhfB_0_pBDcBTCDCHEhMA98DV-SSi6hnn0JgRom6otTQXtcqWt78xqG7fewEZHbzsTbEcFqENwpdWxQz5tnELdQLOOpqm2HeOtq6CroVmYjx-mWDj3b8w2XaLLOdy4Nk7DMTio9SKYk1_tg8nd7WQwTEbj-4fBzSixQrCEYVEYSrFmrMywlNxgzlNZlkbUMiWUFpwawmjNiWCokIJlrCzS2mCJUyI07YOz3ezKu_fWhKhmrvVN96gwIoJnEnf1Pkh2lA3RrNXK26X2G6X9XImUplwNX9_U8xN7zHOC1IR-A0F0cuk</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1026589124</pqid></control><display><type>article</type><title>OR-30: Stress induced impaired pressure natriuresis is associated with an extended period of elevated blood pressure in black youths</title><source>Oxford Journals Online</source><creator>Harshfield, Gregory A. ; Wilson, Martha E. ; Mackey, Lynne ; Gillis, Delores ; Treiber, Frank A. ; Hanevold, Coral D. ; Kapuku, Gaston K.</creator><creatorcontrib>Harshfield, Gregory A. ; Wilson, Martha E. ; Mackey, Lynne ; Gillis, Delores ; Treiber, Frank A. ; Hanevold, Coral D. ; Kapuku, Gaston K.</creatorcontrib><description><![CDATA[Background: Blacks have a greater prevalence of hypertension and associated target organ damage than Whites. Salt and stress are two risk factors that have been associated with these differences. Hypothesis: Stress induced impaired sodium regulation results in an extended period of elevated blood pressure in Blacks. The resulting increased cardiovascular load contributes to the premature development of hypertension in Blacks. Methods: Black youths (n=121; aged 15-18 years) were brought into similar levels of sodium balance. Sodium excretion (UNaV) and systolic blood pressure (SBP) were measured during a one hour stress period which was preceded and followed by two hour rest periods. The subjects were divided into two groups based on the direction of change in UNaV during the stress period: excrete (n = 82); and retain (n = 39). Results: The time by group interactions were significant for both variables (P<0.001). “Excreters” showed a significant stress induced increase in SBP (12 ± 9 vs. 17 ± 10; P<0.001) coupled with a significant increase in UNaV (10 ± 5 vs. 16 ± 7 mEq/hr; P<0.001). Both SBP and UNaV returned to baseline levels following stress. In contrast, for “retainers” the stress induced increase in SBP (113 ± 10 vs. 120 ± 13) was associated with a decrease in UNaV (13 ± 6 vs. 10 ± 6 mEq/hr; P<0.001) which continued to decrease into the first hour following the stress period (7 ± 3 mEq/hr; P <0.01). SBP decreased following stress, but did not return to baseline levels by the end of the second hour following the stress period (117 ± 10; P <0.03). Conclusion: These results support our hypothesis by demonstrating impaired sodium regulation during stress leads to an extended period of elevated blood pressure following stress. Further research is needed to determine if this pattern of response leads to the early development of essential hypertension and its sequelae in Blacks.]]></description><identifier>ISSN: 0895-7061</identifier><identifier>EISSN: 1941-7225</identifier><identifier>DOI: 10.1016/S0895-7061(02)02310-5</identifier><identifier>CODEN: AJHYE6</identifier><language>eng</language><publisher>Oxford: Oxford University Press</publisher><subject>Blood Presure ; Race Differences ; Sodium Regulation</subject><ispartof>American journal of hypertension, 2002-04, Vol.15 (S3), p.14A-14A</ispartof><rights>Copyright Nature Publishing Group Apr 2002</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids></links><search><creatorcontrib>Harshfield, Gregory A.</creatorcontrib><creatorcontrib>Wilson, Martha E.</creatorcontrib><creatorcontrib>Mackey, Lynne</creatorcontrib><creatorcontrib>Gillis, Delores</creatorcontrib><creatorcontrib>Treiber, Frank A.</creatorcontrib><creatorcontrib>Hanevold, Coral D.</creatorcontrib><creatorcontrib>Kapuku, Gaston K.</creatorcontrib><title>OR-30: Stress induced impaired pressure natriuresis is associated with an extended period of elevated blood pressure in black youths</title><title>American journal of hypertension</title><addtitle>AJH</addtitle><description><![CDATA[Background: Blacks have a greater prevalence of hypertension and associated target organ damage than Whites. Salt and stress are two risk factors that have been associated with these differences. Hypothesis: Stress induced impaired sodium regulation results in an extended period of elevated blood pressure in Blacks. The resulting increased cardiovascular load contributes to the premature development of hypertension in Blacks. Methods: Black youths (n=121; aged 15-18 years) were brought into similar levels of sodium balance. Sodium excretion (UNaV) and systolic blood pressure (SBP) were measured during a one hour stress period which was preceded and followed by two hour rest periods. The subjects were divided into two groups based on the direction of change in UNaV during the stress period: excrete (n = 82); and retain (n = 39). Results: The time by group interactions were significant for both variables (P<0.001). “Excreters” showed a significant stress induced increase in SBP (12 ± 9 vs. 17 ± 10; P<0.001) coupled with a significant increase in UNaV (10 ± 5 vs. 16 ± 7 mEq/hr; P<0.001). Both SBP and UNaV returned to baseline levels following stress. In contrast, for “retainers” the stress induced increase in SBP (113 ± 10 vs. 120 ± 13) was associated with a decrease in UNaV (13 ± 6 vs. 10 ± 6 mEq/hr; P<0.001) which continued to decrease into the first hour following the stress period (7 ± 3 mEq/hr; P <0.01). SBP decreased following stress, but did not return to baseline levels by the end of the second hour following the stress period (117 ± 10; P <0.03). Conclusion: These results support our hypothesis by demonstrating impaired sodium regulation during stress leads to an extended period of elevated blood pressure following stress. Further research is needed to determine if this pattern of response leads to the early development of essential hypertension and its sequelae in Blacks.]]></description><subject>Blood Presure</subject><subject>Race Differences</subject><subject>Sodium Regulation</subject><issn>0895-7061</issn><issn>1941-7225</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><recordid>eNpNjUtLAzEAhIMoWKs_QQh40cNq3rvxJkWtWim4PYiXkN3N0vSxqUlW27s_3K0V8TTD8M0MAKcYXWKExVWOMsmTFAl8jsgFIhSjhO-BHpYMJykhfB_0_pBDcBTCDCHEhMA98DV-SSi6hnn0JgRom6otTQXtcqWt78xqG7fewEZHbzsTbEcFqENwpdWxQz5tnELdQLOOpqm2HeOtq6CroVmYjx-mWDj3b8w2XaLLOdy4Nk7DMTio9SKYk1_tg8nd7WQwTEbj-4fBzSixQrCEYVEYSrFmrMywlNxgzlNZlkbUMiWUFpwawmjNiWCokIJlrCzS2mCJUyI07YOz3ezKu_fWhKhmrvVN96gwIoJnEnf1Pkh2lA3RrNXK26X2G6X9XImUplwNX9_U8xN7zHOC1IR-A0F0cuk</recordid><startdate>200204</startdate><enddate>200204</enddate><creator>Harshfield, Gregory A.</creator><creator>Wilson, Martha E.</creator><creator>Mackey, Lynne</creator><creator>Gillis, Delores</creator><creator>Treiber, Frank A.</creator><creator>Hanevold, Coral D.</creator><creator>Kapuku, Gaston K.</creator><general>Oxford University Press</general><scope>BSCLL</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope></search><sort><creationdate>200204</creationdate><title>OR-30: Stress induced impaired pressure natriuresis is associated with an extended period of elevated blood pressure in black youths</title><author>Harshfield, Gregory A. ; Wilson, Martha E. ; Mackey, Lynne ; Gillis, Delores ; Treiber, Frank A. ; Hanevold, Coral D. ; Kapuku, Gaston K.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-i664-416be331a44c81995e15579cce6f97233b53e243f52640b96484cb7fe191726a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Blood Presure</topic><topic>Race Differences</topic><topic>Sodium Regulation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Harshfield, Gregory A.</creatorcontrib><creatorcontrib>Wilson, Martha E.</creatorcontrib><creatorcontrib>Mackey, Lynne</creatorcontrib><creatorcontrib>Gillis, Delores</creatorcontrib><creatorcontrib>Treiber, Frank A.</creatorcontrib><creatorcontrib>Hanevold, Coral D.</creatorcontrib><creatorcontrib>Kapuku, Gaston K.</creatorcontrib><collection>Istex</collection><collection>ProQuest Central (Corporate)</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><jtitle>American journal of hypertension</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Harshfield, Gregory A.</au><au>Wilson, Martha E.</au><au>Mackey, Lynne</au><au>Gillis, Delores</au><au>Treiber, Frank A.</au><au>Hanevold, Coral D.</au><au>Kapuku, Gaston K.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>OR-30: Stress induced impaired pressure natriuresis is associated with an extended period of elevated blood pressure in black youths</atitle><jtitle>American journal of hypertension</jtitle><addtitle>AJH</addtitle><date>2002-04</date><risdate>2002</risdate><volume>15</volume><issue>S3</issue><spage>14A</spage><epage>14A</epage><pages>14A-14A</pages><issn>0895-7061</issn><eissn>1941-7225</eissn><coden>AJHYE6</coden><abstract><![CDATA[Background: Blacks have a greater prevalence of hypertension and associated target organ damage than Whites. Salt and stress are two risk factors that have been associated with these differences. Hypothesis: Stress induced impaired sodium regulation results in an extended period of elevated blood pressure in Blacks. The resulting increased cardiovascular load contributes to the premature development of hypertension in Blacks. Methods: Black youths (n=121; aged 15-18 years) were brought into similar levels of sodium balance. Sodium excretion (UNaV) and systolic blood pressure (SBP) were measured during a one hour stress period which was preceded and followed by two hour rest periods. The subjects were divided into two groups based on the direction of change in UNaV during the stress period: excrete (n = 82); and retain (n = 39). Results: The time by group interactions were significant for both variables (P<0.001). “Excreters” showed a significant stress induced increase in SBP (12 ± 9 vs. 17 ± 10; P<0.001) coupled with a significant increase in UNaV (10 ± 5 vs. 16 ± 7 mEq/hr; P<0.001). Both SBP and UNaV returned to baseline levels following stress. In contrast, for “retainers” the stress induced increase in SBP (113 ± 10 vs. 120 ± 13) was associated with a decrease in UNaV (13 ± 6 vs. 10 ± 6 mEq/hr; P<0.001) which continued to decrease into the first hour following the stress period (7 ± 3 mEq/hr; P <0.01). SBP decreased following stress, but did not return to baseline levels by the end of the second hour following the stress period (117 ± 10; P <0.03). Conclusion: These results support our hypothesis by demonstrating impaired sodium regulation during stress leads to an extended period of elevated blood pressure following stress. Further research is needed to determine if this pattern of response leads to the early development of essential hypertension and its sequelae in Blacks.]]></abstract><cop>Oxford</cop><pub>Oxford University Press</pub><doi>10.1016/S0895-7061(02)02310-5</doi></addata></record>
fulltext fulltext
identifier ISSN: 0895-7061
ispartof American journal of hypertension, 2002-04, Vol.15 (S3), p.14A-14A
issn 0895-7061
1941-7225
language eng
recordid cdi_proquest_journals_1026589124
source Oxford Journals Online
subjects Blood Presure
Race Differences
Sodium Regulation
title OR-30: Stress induced impaired pressure natriuresis is associated with an extended period of elevated blood pressure in black youths
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-26T21%3A19%3A40IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_istex&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=OR-30:%20Stress%20induced%20impaired%20pressure%20natriuresis%20is%20associated%20with%20an%20extended%20period%20of%20elevated%20blood%20pressure%20in%20black%20youths&rft.jtitle=American%20journal%20of%20hypertension&rft.au=Harshfield,%20Gregory%20A.&rft.date=2002-04&rft.volume=15&rft.issue=S3&rft.spage=14A&rft.epage=14A&rft.pages=14A-14A&rft.issn=0895-7061&rft.eissn=1941-7225&rft.coden=AJHYE6&rft_id=info:doi/10.1016/S0895-7061(02)02310-5&rft_dat=%3Cproquest_istex%3E2712863641%3C/proquest_istex%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-i664-416be331a44c81995e15579cce6f97233b53e243f52640b96484cb7fe191726a3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1026589124&rft_id=info:pmid/&rfr_iscdi=true