G017: Why do Afro-Caribbeans have a low incidence of ischaemic heart disease?

Afro-Caribbeans have a greater prevalence of diabetes, hypertension, left ventricular hypertrophy and obesity compared with White Europeans. In spite of this, they have a lower prevalence of ischaemic heart disease. An increased carotid intima-media thickness (IMT) has recently been found to be asso...

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Bibliographic Details
Published in:American journal of hypertension 2000-04, Vol.13 (S2), p.258A-259A
Main Authors: Mayet, J., Chapman, N., Hughes, A.D., Thom, SAMcG, Stanton, A.V.
Format: Article
Language:English
Subjects:
Carotid
ethnicity
hypertrophy
intima-media thickness
Online Access:Get full text
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Summary:Afro-Caribbeans have a greater prevalence of diabetes, hypertension, left ventricular hypertrophy and obesity compared with White Europeans. In spite of this, they have a lower prevalence of ischaemic heart disease. An increased carotid intima-media thickness (IMT) has recently been found to be associated with the majority of known cardiovascular risk factors, including left ventricular hypertrophy. It is widely believed that intima-media thickening may represent an early marker for the development of atheroma. Afro-Caribbean subjects with their clustering of cardiovascular risk factors may be expected to have an increased IMT compared with White Europeans. In order to test this hypothesis 32 age, sex and blood pressure matched Black and White hypertensives underwent bilateral common carotid and femoral ultrasonography and echocardiography. The Afro-Caribbean group had a significantly greater left ventricular mass index compared with the White Europeans (mean±SEM 137±7.3 versus 115±8.5 g/m2, p
ISSN:0895-7061
1941-7225
1879-1905
DOI:10.1016/S0895-7061(00)00978-X