Asymmetric Synthesis of Novel Structural Mimics of Sulphidoleukotrienes

An asymmetric synthetic route toward a new class of structural mimics of the sulphidoleukotrienes has been developed. The key steps in the overall synthetic sequence include Sharpless asymmetric epoxidation followed by stereo- and regioselective opening of the epoxide ring.

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Bibliographic Details
Published in:Chemistry letters 1997-01, Vol.26 (1), p.15-16
Main Authors: Ovaska, Timo V, Voynov, George H, McNeil, Nicole, Hokkanen, Joel A
Format: Article
Language:English
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Summary:An asymmetric synthetic route toward a new class of structural mimics of the sulphidoleukotrienes has been developed. The key steps in the overall synthetic sequence include Sharpless asymmetric epoxidation followed by stereo- and regioselective opening of the epoxide ring.
ISSN:0366-7022
1348-0715
DOI:10.1246/cl.1997.15