Compensation Effect between Differential Activation Enthalpy and Entropy in Subtilisin-Catalyzed Kinetic Resolutions of Secondary Alcohols

Thermodynamic parameters for subtilisin-catalyzed kinetic resolutions of secondary alcohols were determined, and a compensation effect between ΔΔH‡ and ΔΔS‡ was found. These data are explained in terms of the transition-state model.

Saved in:
Bibliographic Details
Published in:Chemistry letters 2000, Vol.29 (7), p.782-783
Main Authors: Ema, Tadashi, Yamaguchi, Kunihiro, Wakasa, Yuji, Tanaka, Nobuaki, Utaka, Masanori, Sakai, Takashi
Format: Article
Language:English
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Thermodynamic parameters for subtilisin-catalyzed kinetic resolutions of secondary alcohols were determined, and a compensation effect between ΔΔH‡ and ΔΔS‡ was found. These data are explained in terms of the transition-state model.
ISSN:0366-7022
1348-0715
DOI:10.1246/cl.2000.782