Study of Poles apart Properties and Appliances of Colloidal Dispersion

• Published in: Research journal of pharmacy and technology 2013-12, Vol.6 (12), p.1402-1412
• Main Authors: Bagade, O. M, Dhole, S. N, Bhargude, D. N, Bhosale, D. R, Kad, D. R, Kahane, S. K
• Format: Article
• Language: English
• Subjects: Absorption; Colloidal dispersion; Properties; Solubility; Stability
• ISSN: 0974-3618; 0974-360X; 0974-306X

Colloidal system is a dispersion wherein dispersed particles i.e. internal phase are distributed uniformly in a dispersion medium i.e. external phase or continuous phase. The size range consume the nanometer (10–9m) to micrometer (10–6m) rang. Dispersed system consist of particulate matter (dispersed phase) and dispersion medium (continuous medium). Classifications of dispersion system according to particle size are molecular dispersion, colloidal and coarse dispersion. Colloidal dispersion is classified into three types lyophilic, lyophobic and association colloids. Surfactant are use to increase stability of colloid. Colloidal dispersion is safe and improves the therapeutic efficacy. Solubility of drug is improved by colloidal system containing surface active agents. This article represents more recent emphasis on the poles apart properties of colloidal dispersion and its solubility, stability, characteristics of dispersed phase as well as medium. It mainly spotlights the appliance and traits of colloidal dispersion to form craving dosage form to give desire biological activities. In a stable dispersion the particle collisions do not lead to aggregation because inter-particle repulsion forces dominate. Poorly water soluble drugs are normally solubalised in aqueous solution by employing association colloids. Usually colloidal system is found due to the nature of the substances dissolved in the media and does not depend on aggregation, chemical nature and origin.