Fat mass and obesity-associated gene (FTO) is associated to eating disorders susceptibility and moderates the expression of psychopathological traits

Eating Disorders (EDs) show a multifactorial etiopathogenesis including environmental, psychological and biological factors. In the present study, we propose a model of interactions between genetic vulnerability-represented by Fat Mass and Obesity-Associated (FTO) gene-and stable psychopathological...

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Bibliographic Details
Published in:PloS one 2017-03, Vol.12 (3), p.e0173560
Main Authors: Castellini, Giovanni, Franzago, Marica, Bagnoli, Silvia, Lelli, Lorenzo, Balsamo, Michela, Mancini, Milena, Nacmias, Benedetta, Ricca, Valdo, Sorbi, Sandro, Antonucci, Ivana, Stuppia, Liborio, Stanghellini, Giovanni
Format: Article
Language:English
Subjects:
Adolescent
Adult
Alleles
Alpha-Ketoglutarate-Dependent Dioxygenase FTO - genetics
Alpha-Ketoglutarate-Dependent Dioxygenase FTO - metabolism
Analysis
Anorexia
Binge-Eating Disorder - genetics
Binge-Eating Disorder - metabolism
Binge-Eating Disorder - psychology
Biology and Life Sciences
Body fat
Brain research
Bulimia
Childrens health
Development and progression
Disorders
Eating
Eating behavior
Eating disorders
Emotional behavior
Fats
Female
Food habits
Gastrointestinal surgery
Gene expression
Gene Expression Regulation
Gene polymorphism
Genes
Genetic aspects
Genetic Predisposition to Disease
Genotypes
Health aspects
Health sciences
Humans
Male
Medicine
Medicine and Health Sciences
Middle Aged
Neurosciences
Obesity
Pathogenesis
Patients
Polymorphism
Polymorphism, Genetic
Psychology
Psychopathology
Quantitative Trait, Heritable
Risk Factors
Single-nucleotide polymorphism
Social Sciences
Studies
Weight control
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