NADPH Oxidases: Insights into Selected Functions and Mechanisms of Action in Cancer and Stem Cells

NADPH oxidases (NOX) are reactive oxygen species- (ROS-) generating enzymes regulating numerous redox-dependent signaling pathways. NOX are important regulators of cell differentiation, growth, and proliferation and of mechanisms, important for a wide range of processes from embryonic development, t...

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Bibliographic Details
Published in:Oxidative medicine and cellular longevity 2017-01, Vol.2017 (2017), p.1-15
Main Authors: Bułdak, Rafał J., Cieslar-Pobuda, Artur, Poterala-Hejmo, Aleksandra, Hejmo, T., Skonieczna, Magdalena
Format: Article
Language:English
Subjects:
Angiogenesis
Antioxidants
Cell Differentiation
Drug dosages
Enzymes
Gene expression
Humans
Kinases
Medicine
Metastasis
NADPH Oxidases - metabolism
Neoplasms - metabolism
Oxidases
Physiological aspects
Physiology
Prostate cancer
Proteins
Radiation therapy
Reactive Oxygen Species - metabolism
Review
Roles
Stem cells
Studies
Transplantation
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