Nickel‐Catalyzed Amination of Aryl Carbamates with Ammonia

Aryl carbamates were employed in the nickel‐catalyzed monoarylation of ammonia. The applied, well‐defined single‐component nickel(II) precatalyst contains a Josiphos ligand, is air‐stable, and operates without any ancillary reductant. This catalyst system also promotes the amination of aryl carbamat...

Full description

Saved in:
Bibliographic Details
Published in:European journal of organic chemistry 2017-06, Vol.2017 (24), p.3496-3500
Main Authors: Schranck, Johannes, Furer, Patrick, Hartmann, Veronika, Tlili, Anis
Format: Article
Language:English
Subjects:
Alkylamines
Amination
Ammonia
Aromatic compounds
Arylation
Carbamates (tradename)
Catalysts
Cross‐coupling
Nickel
Robustness
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Aryl carbamates were employed in the nickel‐catalyzed monoarylation of ammonia. The applied, well‐defined single‐component nickel(II) precatalyst contains a Josiphos ligand, is air‐stable, and operates without any ancillary reductant. This catalyst system also promotes the amination of aryl carbamates with ammonium sulfate as well as with hydrochloride salts of primary alkylamines. Their easy preparation, robustness, and directing group ability makes aryl carbamates particularly attractive synthetic intermediates. The title reaction, is catalyzed by an air‐stable single‐component nickel(II) precatalysts containing a Josiphos ligand. This catalyst system promotes the amination of aryl carbamates with ammonium sulfate as well as with hydrochloride salts of primary alkylamines. Their easy preparation, robustness, and directing‐group ability makes aryl carbamates particularly attractive synthetic intermediates.
ISSN:1434-193X
1099-0690
DOI:10.1002/ejoc.201700660