Nationwide Survey of Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis in Children in the United States

Although Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are serious, life‐threatening reactions to drug therapies, no efforts have been made to investigate the comprehensive change in epidemiology with respect to age, sex, and race and ethnicity in children. The risk of death wa...

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Bibliographic Details
Published in:Pediatric dermatology 2017-03, Vol.34 (2), p.206-208
Main Authors: Okubo, Yusuke, Nochioka, Kotaro, Testa, Marcia A.
Format: Article
Language:English
Subjects:
Adolescent
Child
Child, Preschool
Children
Cross-Sectional Studies
Female
Hospitalization - statistics & numerical data
Humans
Infant
Infant, Newborn
Male
Minority & ethnic groups
Skin diseases
Socioeconomic Factors
Stevens-Johnson syndrome
Stevens-Johnson Syndrome - epidemiology
Surveys and Questionnaires
Toxic epidermal necrolysis
United States - epidemiology
Young Adult
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Summary:Although Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are serious, life‐threatening reactions to drug therapies, no efforts have been made to investigate the comprehensive change in epidemiology with respect to age, sex, and race and ethnicity in children. The risk of death was 0.3% to 1.5%, and the highest hospitalization rates were in children 15 to 19 years of age, boys, and black children. The highest proportions of hospitalizations were children with very low household income, those with private insurance, and those treated at large urban teaching hospitals in the West. A significant winter–autumn predominance was observed.
ISSN:0736-8046
1525-1470
DOI:10.1111/pde.13050