Detecting Signals With Direct Fast Fourier Transform for Microarray Data Collection

Small signals are routinely detected at a frequency away from the 1/f noise. Typically, the signal source is modulated at a suitable frequency, and the harmonics of the modulation frequency in the signal are analyzed with phase sensitive detectors such as Lock-in amplifiers. Yet, the high cost and p...

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Bibliographic Details
Published in:IEEE photonics technology letters 2017-12, Vol.29 (24), p.2211-2214
Main Authors: Chen, Ru, Zhu, Chenggang, Ge, Bilin, Zhu, Xiangdong, Sun, Yung-Shin, Mi, Lan, Ma, Jiong, Wang, Xu, Fei, Yiyan
Format: Article
Language:English
Subjects:
Amplification
Amplifiers
Data acquisition
Fast Fourier transform
Fast Fourier transformations
Fourier transforms
Frequency modulation
Harmonic analysis
Laser beams
lock-in amplifier
Measurement by laser beam
microarray detection
Optical amplifiers
optical biosensor
Phase sensitive detectors
Power harmonic filters
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Summary:Small signals are routinely detected at a frequency away from the 1/f noise. Typically, the signal source is modulated at a suitable frequency, and the harmonics of the modulation frequency in the signal are analyzed with phase sensitive detectors such as Lock-in amplifiers. Yet, the high cost and poor portability of stand-alone Lock-in amplifiers are obstacles to making such an approach of harmonic detection into a widely usable instrumentation. In this letter, we show that for many applications where signals are not too small (e.g., more than tens of micro-volts) the direct fast Fourier transform using a commercially available, general-purpose data acquisition board serves as a cost-effective alternative to Lock-in amplifiers without sacrificing the signal-to-noise ratio.
ISSN:1041-1135
1941-0174
DOI:10.1109/LPT.2017.2771344