Cytoprotective Effects of Cell-Permeable Bifunctional Antioxidant Enzyme, GST-TAT-SOD, against Cisplatin-Induced Cell Damage

GST-TAT-SOD, a cell-permeable bifunctional antioxidant enzyme, is a potential selective radioprotector. This study aimed to investigate the cytoprotective activity of GST-TAT-SOD against cisplatin-induced damage. The current study showed that cisplatin induced the formation of reactive oxygen specie...

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Bibliographic Details
Published in:Oxidative medicine and cellular longevity 2017-01, Vol.2017 (2017), p.1-7
Main Authors: Liu, Shu-Tao, Su, Ying, He, Huocong, Liang, Lili, Li, Lingling, Pan, Jianru, Wang, Xiangling
Format: Article
Language:English
Subjects:
Analysis
Antioxidants
Apoptosis
Bioengineering
Biology
Cancer therapies
Chemotherapy
Cisplatin
Deoxyribonucleic acid
DNA
Enzymes
Free radicals
Free radicals (Chemistry)
Laboratories
Life sciences
Medicine
Proteins
Reactive oxygen species
Rodents
Tumors
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