0132 Oscillating Inspiratory Flow Limitation in Cheyne-Stokes Breathing

Abstract Introduction Cheyne-Stokes breathing (CSB) is thought to be of central rather than obstructive origin. Our aim was to confirm anecdotally observed inspiratory flow limitation (IFL), a marker of obstruction, in CSB. Methods Of 66 774 sleep polygraphs submitted for diagnostic interpretation (...

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Bibliographic Details
Published in:Sleep (New York, N.Y.) N.Y.), 2018-04, Vol.41 (suppl_1), p.A51-A51
Main Authors: Skjodt, N M, Pahwa, V, Platt, R S
Format: Article
Language:English
Subjects:
Automation
Polygraphs
Online Access:Get full text
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Summary:Abstract Introduction Cheyne-Stokes breathing (CSB) is thought to be of central rather than obstructive origin. Our aim was to confirm anecdotally observed inspiratory flow limitation (IFL), a marker of obstruction, in CSB. Methods Of 66 774 sleep polygraphs submitted for diagnostic interpretation (www.sagatech.ca) 30 (0.045%) were reported to have CSB and have acceptable signal quality. Patented breath-by-breath automated IFL scoring of the flow signal was performed. Manual and automated CSB scoring were also applied. Results All 30 polygraphs scored positive for CSB using automated analysis, but only 10 on manual review had oscillating crescendo-decrescendo flow amplitude, alternating apnoea on flow signal, absent snoring, and sinusoidal oximetry. All 10 true positive studies, but none of the 20 false positive tests, had oscillating crescendo-decrescendo IFL. Conclusion Oscillating IFL is ubiquitous in true CSB suggesting mixed central and obstructive origins. CSB detection could be improved by applying both standard definitions and IFL analysis. Support (If Any) None.
ISSN:0161-8105
1550-9109
DOI:10.1093/sleep/zsy061.131