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Synthesis of NiO nanoparticles via a green route using Monsonia burkeana: The physical and biological properties

NiO nanoparticles have emerged as ideal candidates in various fields due to their magnetic, electrical and optical properties. The coupling of plant extracts that have anticancer and antibacterial properties with NiO nanoparticles has increased their usage in the biomedical field. In this work, we r...

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Bibliographic Details
Published in:Journal of photochemistry and photobiology. B, Biology Biology, 2018-05, Vol.182, p.18-26
Main Authors: Kganyago, P., Mahlaule-Glory, L.M., Mathipa, M.M., Ntsendwana, B., Mketo, N., Mbita, Z., Hintsho-Mbita, N.C.
Format: Article
Language:English
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Summary:NiO nanoparticles have emerged as ideal candidates in various fields due to their magnetic, electrical and optical properties. The coupling of plant extracts that have anticancer and antibacterial properties with NiO nanoparticles has increased their usage in the biomedical field. In this work, we report on the novel synthesis of NiO nanoparticles using a local medicinal plant, Monsonia burkenea. The nickel nanoparticles were characterized using Fourier transform infrared spectroscopy (FTIR), Energy dispersive X-ray analysis (EDX), Scanning electron microscope (SEM), High-resolution transmission electron microscope (HRTEM) and X-ray diffraction (XRD). FTIR showed that the extraction of the plant phytochemicals was successful and the green synthesized nanoparticles from plants contained the phytochemical groups that are found in the Monsonia burkeana plant. XRD and HRTEM confirmed the successful formation of NiO nanoparticles with an average particle size range of 20 nm. These results were also corroborated by elemental mapping and EDX, where the dominant groups were identified.The Monsonia burkeana NiO particles exhibited selective bactericidal activity against Gram-negative strains, such as E. coli and P. aeruginosa. Additionally, cytotoxicity studies showed the materials did not have any anti proliferative effect against A549 lung cancer cells but could be used as potential drug delivery vehicles against human cancers. [Display omitted] •NiO nanoparticles were synthesized using Monsonia Burkeana plant extract.•The photocatalytic activity of NiO nanoparticles was determined using methylene blue dye.•Green synthesized NiO were tested against A549 lung cancer cells.•NiO nanoparticles are active against Gram negative bacterial strains.•NiO nanoparticles could be used as a potential drug delivery vehicle.
ISSN:1011-1344
1873-2682
DOI:10.1016/j.jphotobiol.2018.03.016