RRI Children: Preventive Vaccination Issues

• Published in: Biomedical & pharmacology journal 2017, Vol.10 (4), p.2077-2084
• Main Author: Kozhevnikova, Olga A
• Format: Article
• Language: English
• Subjects: Calendars; Children; Children & youth; Cough; Disease prevention; Epidemiology; Hypogammaglobulinemia; Immune response; Immune system; Immunoglobulins; Immunology; Immunoprophylaxis; Infections; Infectious diseases; Laboratories; Measles; Medical technology; Morbidity; Pediatrics; Pertussis; Vaccination; Values
• ISSN: 0974-6242; 2456-2610
• DOI: 10.13005/bpj/1330

Based on the years of experience of immunization against infectious diseases, it is stated that preventive vaccinations should only be given to healthy children. Children with altered reactivity should be vaccinated only if certain conditions are met. However, the vaccination schedule can not be stable. The effectiveness of immunoprophylaxis largely depends on the correct age for primary immunization and optimal intervals between vaccinations taking into account their state of health to exclude disturbances in the course of the vaccination process. The issue of contraindications to the provision of preventive vaccinations is urgent and complex in the problem of preventing infectious diseases. There is a category of children for whom the full immunization schedule provided for healthy children is an unbearable burden. Contraindications to the conduct of a vaccine is determined not only on the basis of the anamnesis, but also on the clinical examination. The ability to react or not to react to any particular antigen, as well as the height of the immune response, are genetically encoded. One of the most important factors that significantly affect the development of children is their morbidity, especially during the first three years of life. Active immunization depends on this factor. About 10% of children do not get vaccinated due to temporary medical contraindications. Although there are only two reasons for withdrawing from vaccinations: hypogammaglobulinemia and a high probability of a severe outcome as a result of vaccination. Difficulties in solving a problem of clinical safety force pediatricians to exclude from immunization most children with the problems in the anamnesis. It prevents the formation of collective immunity among children and creates the danger of a more frequent occurrence of a severe course of infectious diseases (measles, whooping cough) in children with the problems in the anamnesis.