Patient Preferences In The Treatment of Periodontal Disease: Multi-Dimensionality and Validity

OBJECTIVES: Parodontopathies refer to all inflammatory diseases of the tooth retaining apparatus. Various treatments are available for therapy. So far, it is unclear which patient-relevant endpoints determine the benefit of treatments. The aim of the study is to document the relative importance of p...

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Bibliographic Details
Published in:Value in health 2017-10, Vol.20 (9), p.A806
Main Authors: Mühlbacher, AC, Juhnke, C, Sadler, A, Kaczynski, A
Format: Article
Language:English
Subjects:
Attributes
Bleeding
Data processing
Dental caries
Discrete choice
Everyday life
Gum disease
Inflammation
Inflammatory diseases
Medical treatment
Morbidity
Oral diseases
Pain
Patients
Periodontics
Questionnaires
Severity
Side effects
Teeth
Treatment preferences
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Summary:OBJECTIVES: Parodontopathies refer to all inflammatory diseases of the tooth retaining apparatus. Various treatments are available for therapy. So far, it is unclear which patient-relevant endpoints determine the benefit of treatments. The aim of the study is to document the relative importance of patient-relevant endpoints for therapies in periodontal disease. In addition, it will be examined to what extent changing decision criteria influence the validity of Discrete Choice Experiments (DCE). METHODS: Two randomized online-supported DCEs with different decision models were performed. For each model, six patient-relevant endpoints were considered as attributes for morbidity and side effects of the therapy. "Tooth loosening/tooth loss" was presented as a multi-dimensional attribute with varying severity and the number of teeth concerned. The data were analyzed by Random Parameter Logit (RPL) model and Latent Class (LC) model. RESULTS: Data from N=627 participants (Modell:N=309, Model2:N=318) were evaluated. The results of the RPL-model show in both DCEs that decisions were significantly influenced from "tooth loosening/tooth loss" (Modell:Koef.:0.827; Model2:Coef.:0.885). In the two questionnaire versions, the attributes "tooth loosening/tooth loss", "gum bleeding", "pain in everyday life" and "pain by the therapy" occupied the front ranks and influenced the patients benefit most. Significant standard deviations (p
ISSN:1098-3015
1524-4733
DOI:10.1016/j.jval.2017.08.2403