Fatal Bacterial Infections Associated With Platelet Transfusions—United States, 2004

Each year, approximately 9 million platelet-unit concentrates are transfused in the US; an estimated one in 1,000-3,000 platelet units is contaminated with bacteria, resulting in transfusion-associated sepsis in many recipients. To reduce this risk, the American Association of Blood Banks (AABB) has...

Full description

Saved in:
Bibliographic Details
Published in:JAMA : the journal of the American Medical Association 2005-06, Vol.293 (21), p.2586-2591
Main Authors: Arendt, A, Carmean, J, Koch, E, Rolfs, R
Format: Article
Language:English
Subjects:
Bacteria
Blood banks
Blood transfusions
Contamination
Infectious diseases
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Each year, approximately 9 million platelet-unit concentrates are transfused in the US; an estimated one in 1,000-3,000 platelet units is contaminated with bacteria, resulting in transfusion-associated sepsis in many recipients. To reduce this risk, the American Association of Blood Banks (AABB) has adopted a new standard on Mar 1, 2004 that requires blood banks and transfusion services to implement measures to detect and limit bacterial contamination in all platelet components. Here, Arendt et al summarize two fatal cases of transfusion-associated sepsis in platelet recipients in 2004 and describe results of a 2004 survey of infectious-disease consultants regarding their knowledge of transfusion-associated bacterial infections and the new AABB standard. A CDC editorial note is included.
ISSN:0098-7484
1538-3598
DOI:10.1001/jama.293.21.2586