Universidade Federal de Minas Gerais, Hospital das Clínicas, Centro de Referência em Neurofibromatoses, Belo Horizonte MG, Brasil

Psychiatric disorders frequently occur in patients with multiple sclerosis (MS); however, limited reports are available on these comorbidities. We aimed to investigate the relationships among MS, anxiety, depression, and suicidal ideation. Methods: One hundred and thirty two patients with relapsing-...

Full description

Saved in:
Bibliographic Details
Published in:Arquivos de neuro-psiquiatria 2018-05, Vol.76 (5), p.296
Main Authors: Tauil, Carlos Bernardo, Grippe, Talyta Cortez, Dias, Ronaldo Maciel, Dias-Carneiro, Rafael Paternò Castello, Carneiro, Narel Moita, Aguilar, Ana Carolina Rodrigues, da Silva, Flávia Martins, Bezerra, Felipe, de Almeida, Leonardo Kenzo, Massarente, Vitoria Lana, Giovannelli, Elaine de Carvalho, Tilbery, Charles Peter, Brandão, Carlos Otávio, Santos, Leonilda Maria B, dos Santos-Neto, Leopoldo
Format: Article
Language:eng ; por
Subjects:
Anxiety
Genetic disorders
Mental depression
Mental disorders
Multiple sclerosis
Neurological disorders
Self destructive behavior
Suicide
Suicides & suicide attempts
Tumors
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Psychiatric disorders frequently occur in patients with multiple sclerosis (MS); however, limited reports are available on these comorbidities. We aimed to investigate the relationships among MS, anxiety, depression, and suicidal ideation. Methods: One hundred and thirty two patients with relapsing-remitting MS were evaluated using the Expanded Disability Status Scale, Beck Depression Inventory-II (BDI-II), Beck Scale for Suicide Ideation (BSI), and Hospital Anxiety and Depression Scale. Results: A hierarchical regression analysis was performed to evaluate the variables. The regression equation significantly predicted the BSI score (R2 = 0.306; adjusted R2 = 0.273; F (9, 125) = 9.18; p < 0.0005), and the BDI-II score was the only variable that contributed significantly to this model (p < 0.0005). Conclusions: A high prevalence of depression and anxiety, and a higher rate of suicidal ideation were identified in MS patients compared to the general population. The presence of depressive symptoms appeared to have a direct influence on the risk of suicide.
ISSN:0004-282X
1678-4227