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Synthesis of New Tetrazole Derivatives and Their Biological Evaluation
An operationally simple and efficient method of synthesis of novel 1,5-disubstituted tetrazoles with high yields from easily accessible 2-(2-benzamido-3-arylacrylamido)acetate under mild conditions is developed. Anticancer and anti-microbial tests of the new tetrazole derivatives have been carried o...
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Published in: | Russian journal of general chemistry 2018-08, Vol.88 (8), p.1726-1733 |
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container_end_page | 1733 |
container_issue | 8 |
container_start_page | 1726 |
container_title | Russian journal of general chemistry |
container_volume | 88 |
creator | Soliman, H. A. Kalmouch, A. Awad, H. M. Abdel Wahed, N. A. M. |
description | An operationally simple and efficient method of synthesis of novel 1,5-disubstituted tetrazoles with high yields from easily accessible 2-(2-benzamido-3-arylacrylamido)acetate under mild conditions is developed. Anticancer and anti-microbial tests of the new tetrazole derivatives have been carried out. |
doi_str_mv | 10.1134/S1070363218080273 |
format | article |
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subjects | Acetates Anti-infective agents Antiinfectives and antibacterials Chemistry Chemistry and Materials Science Chemistry/Food Science Derivatives Microorganisms Peptides Synthesis Tetrazoles |
title | Synthesis of New Tetrazole Derivatives and Their Biological Evaluation |
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