Thermal, spectroscopic and in vitro antimicrobial analysis of 2, 2′-(2-((carboxymethyl)(2-(2-hydroxyethoxy)-2-oxoethyl)amino)ethylazanediyl)diacetatocobalt(II)/manganese(II) hydrate

• Published in: Journal of thermal analysis and calorimetry 2018-12, Vol.134 (3), p.1965-1973
• Main Authors: Jeya Rajendran, A., Dhawa, Soven, Jeya Jothi, G., Hannah Hepsibah, A.
• Format: Article
• Language: English
• Subjects: Analytical Chemistry; Antiinfectives and antibacterials; Bactericides; Chemistry; Chemistry and Materials Science; Coordination compounds; Ethylenediaminetetraacetic acids; Fourier transforms; Fungicides; Infrared spectroscopy; Inorganic Chemistry; Ligands; Magnetic permeability; Manganese; Measurement Science and Instrumentation; NMR; Nuclear magnetic resonance; Physical Chemistry; Polymer Sciences
• ISSN: 1388-6150; 1588-2926
• DOI: 10.1007/s10973-018-7729-2

Co(II), and Mn(II) complexes using 2,2′-(2-((carboxymethyl)(2-(2-hydroxyethoxy)-2-oxoethyl)amino)ethylazanediyl)diacetato (SCHOEA), derivative of disodium salt of EDTA were synthesized by three stages and characterized by spectroscopic (UV–Visible, FTIR, EPR, 1 H NMR) techniques, magnetic susceptibility measurements and thermal studies (TA). Electronic and magnetic susceptibility measurements indicated low-spin octahedral complexes. The FTIR spectra supported the coordination mode of the ligand as hexadentate with the metal ions. Molar conductivity supported the non-electrolytic nature of the complexes. The EPR spectra confirmed the distorted octahedral geometry of the complexes based on the computation of Hamiltonian parameters and the degree of covalency. In vitro antimicrobial activities of the ligand and metal complexes against three bacterial ( Enterobacteraerogenes , Micrococcus luteus , Shigellaflexineria ) and two fungal species ( Candida albicans , Aspergillusflavus ) were performed by disc diffusion method which revealed that the complexes are more potent bactericides and fungicides than the ligand.