NECROTIZING FASCIITIS OF THE MALE GENITAL REGION – A REVIEW OF THE LITERATURE

Thrombosis of the nutrient vessels with secondary reduction in blood flow to the region involved leads to tissue ischaemia, promoting further anaerobic bacteria proliferation, that may produce enzymes which lead to digestion of fascial barriers. CBC with differential count, electrolytes, BUN, creati...

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Published in:Research and science today 2018-01, p.24
Main Authors: Iorga, Lucian, Anghel, Radu, Manea, Maria, Marcu, Dragoş, Socea, Bogdan, Diaconu, Camelia, Bratu, Ovidiu, Băleanu, Vlad-Dumitru, Mischianu, Dan
Format: Article
Language:English
Subjects:
Acidosis
Adjuncts
Aminoglycosides
Anaerobic bacteria
Biodegradation
Blood flow
Blood vessels
Coagulation
Contamination
Creatinine
Culture
Defects
Diabetes
Diabetic neuropathy
Disseminated intravascular coagulation
Dressings
Electrolytes
Fasciitis
Fibrin
Fibrinogen
Gangrene
Genitalia
Heart failure
HIV
Human immunodeficiency virus
Hyperbaric oxygen therapy
Hyperglycemia
Hypoglycemia
Immune system
Infections
Iodine
Ischemia
Literature reviews
Males
Medical imaging
Metronidazole
Mortality
Necrotizing fasciitis
Nutrient flow
Pathogenesis
Patients
Penicillin
Povidone
Risk factors
Sepsis
Therapy
Thromboembolism
Thrombosis
Urine
Wound healing
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Summary:Thrombosis of the nutrient vessels with secondary reduction in blood flow to the region involved leads to tissue ischaemia, promoting further anaerobic bacteria proliferation, that may produce enzymes which lead to digestion of fascial barriers. CBC with differential count, electrolytes, BUN, creatinine, blood glucose levels, acidosis with hyperglycemia or hypoglycemia may be present, ABG sampling for a more accurate assessment of acid/base disturbance, blood and urine cultures, disseminated intravascular coagulation (DIC) panel (coagulation studies, fibrinogen/fibrin degradation product levels) to find evidence of severe sepsis, cultures of any open wound and abscess. [...]generation cefalosporins or aminoglycosides, plus penicillin and metronidazole can be used, usually in the clasically triple therapy. Surgical adjuncts such as fecal and urinary diversion, where continuous contamination would affect wound healing, vacuum assisted closure, topical agents (sodium hypochloride solutions, povidone iodine dressings, fibrin glue) and hyperbaric oxygen therapy have all been used with great results.
ISSN:2247-4455
2285-9632