Low Bone Mineral Density, HIV Infection, and Women: Fracture or Fiction?

[2] that compared HIV-positive, predominantly antiretroviral-experienced, premenopausal women with healthy control subjects, the association between HIV status and osteopenia remained significant after controlling for known risk factors for low BMD, such as age, race, menstrual function, and weight...

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Bibliographic Details
Published in:Clinical infectious diseases 2006-04, Vol.42 (7), p.1021-1023
Main Authors: Yin, Michael T., Glesby, Marshall J.
Format: Article
Language:English
Subjects:
Anti-HIV Agents - adverse effects
Bone Density
Bones
Cytokines - biosynthesis
Estrogens - deficiency
Female
Fractures, Bone - etiology
HIV
HIV Infections - drug therapy
HIV Infections - immunology
HIV Infections - metabolism
Human immunodeficiency virus
Humans
Menopause
Osteoporosis
Women
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Summary:[2] that compared HIV-positive, predominantly antiretroviral-experienced, premenopausal women with healthy control subjects, the association between HIV status and osteopenia remained significant after controlling for known risk factors for low BMD, such as age, race, menstrual function, and weight or body mass index. [17] report the results of a large cross-sectional study of BMD in perimenopausal, HIV-positive women recruited as part of the Ms. Study, a longitudinal study of menopause and its sequelae in women either with or at risk for HIV infection. In non-black women, multivariate analyses found that age, weight, and HIV infection were independently associated with reduced femoral neck and lumbar spine BMD.
ISSN:1058-4838
1537-6591
DOI:10.1086/501025