GP200 Is the influenza in neonates a dangerous infection? – own observations

BackgroundInfluenza is a viral infectious disease affecting every age group, including neonates and infants.AimTo analyze the frequency, clinical signs and course of influenza in neonates hospitalized during three influenza epidemic seasons.Material and Methods12 neonates were hospitalized due to in...

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Bibliographic Details
Published in:Archives of disease in childhood 2019-06, Vol.104 (Suppl 3), p.A111
Main Authors: Zawłocka, Edyta, Czajkowska, Małgorzata, Wrotek, August, Jackowska, Teresa
Format: Article
Language:English
Subjects:
Childrens health
Communicable Diseases
Cough
Diagnostic Tests
Dyspnea
Epidemics
Fever
Hospitalization
Infants
Infectious diseases
Influenza
Influenza A
Influenza B
Neonates
Newborn babies
Patients
Pediatrics
Polymerase chain reaction
Public health
Respiration
Rhinitis
Seasons
Vaccination
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Summary:BackgroundInfluenza is a viral infectious disease affecting every age group, including neonates and infants.AimTo analyze the frequency, clinical signs and course of influenza in neonates hospitalized during three influenza epidemic seasons.Material and Methods12 neonates were hospitalized due to influenza in Department of Pediatrics in three influenza epidemic seasons. Rapid Influenza Diagnostic Tests (RIDTs) and/or Real Time-Polymerase Chains Reaction Tests (RT-PCR) were performed in patients with a clinical suspicion of influenza.ResultsFrom September 2015 to August 2018 we hospitalized 294 patients with influenza. The youngest patient was 12 days old, the oldest – 17 years 3 months. 4.1% (12/294) were neonates. The most common reason for hospital referral was fever (58.3%; 7/12). Other observe symptoms were: coryza (58.3%; 7/12), change of behavior (58.3%; 7/12), cough (50%; 6/12), dyspnea (40%; 5/12) and apneas (8.3%; 1/12). RIDTs were performed in seven (58.3%) of neonates, but positive results were only in 2 cases (16%). The final diagnosis was made using RT-PCR tests. 83.3% (10/12) of neonates were diagnosed with influenza A, and 1.7% (2/12) influenza B. Complications occurred in eight neonates. 75% (9/12) patients had contact with the infection at home. None of the families were influenza-vaccinated before the season. The average time of hospitalization was 10.2 days (from 6 to 15 days).ConclusionThe course of influenza in neonates can be severe. RIDTs seem not very useful in diagnose.This study was supported by CMKP. Grant number 501–1–-20–19–18
ISSN:0003-9888
1468-2044
DOI:10.1136/archdischild-2019-epa.260