Development and Validation for estimation of Abiraterone acetate in Bulk and Pharmaceutical Dosage Form by UPLC

Mobile phase 0.01N NaHPO4: Acetonitrile in the ratio of 60:40v/v and flow rate were maintained at 0.3 ml/min, detection wave length was 235 nm, and column temperature was set to 30°C. System suitability parameters were studied by injecting the standard six times and results were well under the accep...

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Bibliographic Details
Published in:Research journal of pharmacy and technology 2019, Vol.12 (6), p.3029-3032
Main Authors: Goud, V. Mohan, Rani, B Sandhya, Sharma, JVC, Sirisha, P.
Format: Article
Language:English
Subjects:
Chromatography
Ions
Prostate cancer
Studies
Online Access:Get full text
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Summary:Mobile phase 0.01N NaHPO4: Acetonitrile in the ratio of 60:40v/v and flow rate were maintained at 0.3 ml/min, detection wave length was 235 nm, and column temperature was set to 30°C. System suitability parameters were studied by injecting the standard six times and results were well under the acceptance criteria. [...]our plan to develop a new economic UPLC method for routine analysis. Khdera A, Darwish I, Bamanea F, Analysis of abiraterone stress degradation behavior using liquid chromatography coupled to ultraviolet detection and electrospray ionization mass spectrometry.
ISSN:0974-3618
0974-360X
0974-306X
DOI:10.5958/0974-360X.2019.00512.2