Inadequacies of Self-Report Data for Exclusion Criteria Detection in Marihuana Research: An Empirical Case for Multi-Method Direct Examination Screening

Stringent exclusion criteria in drug abuse research are necessary to protect against methodological confounds compromising the interpretation of findings. However, reliance on self-report screening may fail to detect important exclusion variables. We compared three levels of exclusion criteria scree...

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Bibliographic Details
Published in:Journal of addictive diseases 2000-10, Vol.19 (3), p.71-87
Main Authors: Struve, Frederick A., Straumanis, John J., Manno, Joseph E., Fitzgerald, Mary-Jo, Patrick, Gloria, Leavitt, John
Format: Article
Language:English
Subjects:
Addictive behaviors
Adolescent
Adult
Adult and adolescent clinical studies
Biological and medical sciences
Brain - physiology
Cost-Benefit Analysis
Data collection
Drug abuse
drug abuse exclusions
Drug addiction
Drug addictions
drug screen
Drug testing
Electroencephalography
Evoked Potentials - physiology
Exclusion criteria
Female
Humans
Male
marihuana
Marijuana
Marijuana Abuse - diagnosis
Marijuana Abuse - economics
Marijuana Abuse - epidemiology
medical exclusions
Medical sciences
psychiatric exclusions
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Self evaluation
Self-Assessment
Social research
Substance Abuse Detection
Toxicology
Validity
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Summary:Stringent exclusion criteria in drug abuse research are necessary to protect against methodological confounds compromising the interpretation of findings. However, reliance on self-report screening may fail to detect important exclusion variables. We compared three levels of exclusion criteria screening in a study of neurophysiological/neurocognitive sequelae of chronic marihuana use in normals. LEVEL 1 (self-report) consisted of telephone pre-screening. LEVEL 2 (also self-report) involved in-depth personal interviews. LEVEL 3 consisted of several direct examination assessments including a medical/psychiatric examination by a board certified psychiatrist, eight weeks of twice per week urine drug screens, an EEG exam and eight hours of neuropsychological testing. Results indicated that 39.0% of subjects passing self-report screening had significant exclusion criteria findings that were only detected through LEVEL 3 direct examination procedures. Of all subjects found to have exclusion criteria after being provisionally accepted following LEVEL 1 telephone pre-screening, 55.7% were detected only through more rigorous LEVEL 3 direct examination screening methods.
ISSN:1055-0887
1545-0848
DOI:10.1300/J069v19n03_06