Epidemiology and outcomes of community-acquired and hospital-acquired acute kidney injury in children and adolescents

Background Hospital-acquired acute kidney injury (HA-AKI) is associated with an increased risk of childhood mortality; however, only a few studies have addressed community-acquired AKI (CA-AKI). Methods AKI network classification was used to assess CA- and HA-AKI, 2010–2014. Patients with CA-AKI who...

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Bibliographic Details
Published in:Pediatric research 2018-03, Vol.83 (3), p.622-629
Main Authors: Hsu, Chien-Ning, Chen, Hsiao-Ling, Tain, You-Lin
Format: Article
Language:English
Subjects:
692/499
692/699/1585/4
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692/700/478/174
Children & youth
Clinical outcomes
clinical-investigation
Epidemiology
Kidney diseases
Kidneys
Medicine
Medicine & Public Health
Mortality
Patient admissions
Pediatric Surgery
Pediatrics
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Summary:Background Hospital-acquired acute kidney injury (HA-AKI) is associated with an increased risk of childhood mortality; however, only a few studies have addressed community-acquired AKI (CA-AKI). Methods AKI network classification was used to assess CA- and HA-AKI, 2010–2014. Patients with CA-AKI who were admitted to an inpatient setting were categorized as CAA-AKI. CANA-AKI was for CA-AKI not admitted to inpatient care. Epidemiology, factors associated with AKI, and in-hospital outcomes were assessed for variation. Results Prevalence of CANA-AKI was 4/1,000 outpatient visits, 17/1,000 hospital admissions for CAA-AKI, and 9.69/1,000 hospital admissions for HA-AKI. Mortality was higher among AKI patients (HA-AKI, 13.64%; CAA-AKI, 3.7%) than in no-AKI patients (0.57%). Patients with AKI and those with severe stages of AKI resulted in an increase in health-care service utilization (both P
ISSN:0031-3998
1530-0447
DOI:10.1038/pr.2017.262