Perinatal Micro-Bleeds and Neuroinflammation in E19 Rat Fetuses Exposed to Utero-Placental Ischemia

Offspring of preeclampsia patients have an increased risk of developing neurological deficits and cognitive impairment. While low placental perfusion, common in preeclampsia and growth restriction, has been linked to neurological deficits, a causative link is not fully established. The goal of this...

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Bibliographic Details
Published in:International journal of molecular sciences 2019-08, Vol.20 (16), p.4051
Main Authors: Giambrone, Ashtin B., Logue, Omar C., Shao, Qingmei, Bidwell, Gene L., Warrington, Junie P.
Format: Article
Language:English
Subjects:
Animals
Blood pressure
Blood Pressure - physiology
Brain
Chemokine CCL11 - metabolism
Chemokine CXCL2 - metabolism
Chemokine CXCL5 - metabolism
Chemokines
Cognitive ability
Cytokines
Edema
Female
Fetus - metabolism
Fetuses
Growth factors
Inflammation - metabolism
Interleukin-18 - metabolism
Interleukin-1beta - metabolism
Interleukin-6 - metabolism
Ischemia
Ischemia - metabolism
Male
Microglia - metabolism
Morphology
Placenta - metabolism
Preeclampsia
Pregnancy
Rats
Rats, Sprague-Dawley
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