Drop coating deposition Raman scattering of selected small molecules of biological importance

Drop coating deposition Raman scattering spectroscopy was used to study selected small biologically important molecules. This technique combines the advantages of low concentrations and small volumes of the initial aqueous solution. Detection limits were found to be 10−6, 10−7, and 10−8 M deposition...

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Bibliographic Details
Published in:Journal of Raman spectroscopy 2020-05, Vol.51 (5), p.871-874
Main Authors: Kočišová, Eva, Sayedová, Shirin, Procházka, Marek
Format: Article
Language:English
Subjects:
Acetylsalicylic acid
Aqueous solutions
Deposition
Detection limits
drop coating deposition Raman
Low concentrations
Methylene blue
Raman spectra
Raman spectroscopy
Riboflavin
Silver
Spectroscopy
Spectrum analysis
Substrates
surface‐enhanced Raman
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Summary:Drop coating deposition Raman scattering spectroscopy was used to study selected small biologically important molecules. This technique combines the advantages of low concentrations and small volumes of the initial aqueous solution. Detection limits were found to be 10−6, 10−7, and 10−8 M deposition concentration for riboflavin, acetylsalicylic acid, and methylene blue, respectively. These detection limits are comparable or even better than those of surface‐enhanced Raman scattering (SERS) spectroscopy using commercial Ag substrate. Drop coating deposition Raman scattering (DCDRS) spectroscopy was used to study selected small biologically important molecules. Detection limits were found to be 10−6, 10−7, and 10−8 M deposition concentration for riboflavin, acetylsalicylic acid, and methylene blue, respectively. These detection limits are comparable or even better than those of surface‐enhanced Raman scattering (SERS) spectroscopy using commercial Ag substrate.
ISSN:0377-0486
1097-4555
DOI:10.1002/jrs.5840