Synthetic Biology and Genome-Editing Tools for Improving PHA Metabolic Engineering

Polyhydroxyalkanoates (PHAs) are a diverse family of biopolyesters synthesized by many natural or engineered bacteria. Synthetic biology and DNA-editing approaches have been adopted to engineer cells for more efficient PHA production. Recent advances in synthetic biology applied to improve PHA biosy...

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Bibliographic Details
Published in:	Trends in biotechnology (Regular ed.) 2020-07, Vol.38 (7), p.689-700
Main Authors:	Zhang, Xu, Lin, Yina, Wu, Qiong, Wang, Ying, Chen, Guo-Qiang
Format:	Article
Language:	English
Subjects:	Binding sites Biology biopolyesters Biosynthesis Carbon Cell growth Cell morphology cell structures CRISPR CRISPR-associated proteins Cytology Deoxyribonucleic acid Design DNA E coli Editing Escherichia coli Fatty acids gene editing Gene expression Genetic engineering genetically engineered microorganisms Genome editing Genomes Halomonas Internal Medicine Metabolic engineering Metabolic flux Metabolism Microorganisms molecular weight Morphology Optimization Plasmids Polyhydroxyalkanoates RNA polymerase Stability Synthetic biology
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