Effect of intranasal oxytocin on the core social symptoms of autism spectrum disorder: a randomized clinical trial

Although small-scale studies have described the effects of oxytocin on social deficits in autism spectrum disorder (ASD), no large-scale study has been conducted. In this randomized, parallel-group, multicenter, placebo-controlled, double-blind trial in Japan, 106 ASD individuals (18–48 y.o.) were e...

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Published in:	Molecular psychiatry 2020-08, Vol.25 (8), p.1849-1858
Main Authors:	Yamasue, Hidenori, Okada, Takashi, Munesue, Toshio, Kuroda, Miho, Fujioka, Toru, Uno, Yota, Matsumoto, Kaori, Kuwabara, Hitoshi, Mori, Daisuke, Okamoto, Yuko, Yoshimura, Yuko, Kawakubo, Yuki, Arioka, Yuko, Kojima, Masaki, Yuhi, Teruko, Owada, Keiho, Yassin, Walid, Kushima, Itaru, Benner, Seico, Ogawa, Nanayo, Eriguchi, Yosuke, Kawano, Naoko, Uemura, Yukari, Yamamoto, Maeri, Kano, Yukiko, Kasai, Kiyoto, Higashida, Haruhiro, Ozaki, Norio, Kosaka, Hirotaka
Format:	Article
Language:	English
Subjects:	631/378 692/699/476/1373 Administration, Intranasal Adolescent Adult Autism Autism Spectrum Disorder - drug therapy Autism Spectrum Disorder - physiopathology Autism Spectrum Disorder - psychology Behavioral Sciences Biological Psychology Clinical trials Double-Blind Method Gynecomastia Gynecomastia - chemically induced Humans Japan Male Medical colleges Medicine Medicine & Public Health Middle Aged Neurosciences Oxytocin Oxytocin - administration & dosage Oxytocin - adverse effects Oxytocin - blood Oxytocin - therapeutic use Patient compliance Pharmacotherapy Placebos Psychiatry Young Adult
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