Pharmacogenetics of Carbamazepine and Valproate: Focus on Polymorphisms of Drug Metabolizing Enzymes and Transporters

Pharmacogenomics can identify polymorphisms in genes involved in drug pharmacokinetics and pharmacodynamics determining differences in efficacy and safety and causing inter-individual variability in drug response. Therefore, pharmacogenomics can help clinicians in optimizing therapy based on patient...

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Bibliographic Details
Published in:Pharmaceuticals (Basel, Switzerland) Switzerland), 2021-03, Vol.14 (3), p.204
Main Authors: Iannaccone, Teresa, Sellitto, Carmine, Manzo, Valentina, Colucci, Francesca, Giudice, Valentina, Stefanelli, Berenice, Iuliano, Antonio, Corrivetti, Giulio, Filippelli, Amelia
Format: Article
Language:English
Subjects:
Anticonvulsants
Biomarkers
Bipolar disorder
carbamazepine
Convulsions & seizures
Drugs
Enzymes
Epilepsy
Genes
Mental depression
Mental disorders
Metabolism
Metabolites
mood stabilizers
Patients
pharmacogenomics
Phosphorylation
Psychotropic drugs
Review
valproate
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