0312 Performance on a Cognitive Interference Task in Children After One-Night of Sleep Restriction

• Published in: Sleep (New York, N.Y.) N.Y.), 2020-05, Vol.43 (Supplement_1), p.A117-A118
• Main Authors: de Queiroz Campos, G, Dickstein, D P, Carskadon, M A, Saletin, J M
• Format: Article
• Language: English
• Subjects: Sleep deprivation
• ISSN: 0161-8105; 1550-9109
• DOI: 10.1093/sleep/zsaa056.309

Abstract Introduction Short sleep contributes to attention failure in conditions such as ADHD. Whether sleep loss affects attentional processes as a task varies in cognitive interference is unclear. We used a multi-source interference task (MSIT) in a sleep restriction paradigm in children with a range of ADHD symptoms to examine how short sleep disrupts attention in these youth. Methods Thirteen children (7F, 11.7±1.28 years) with a range of ADHD symptom severity completed a repeated-measures experiment on two consecutive nights in the laboratory: baseline (BSLN; 9.5h time-in-bed) and sleep restriction (SR; 4h time-in-bed). Each morning they took part in an fMRI session including the MSIT, in which participants respond to a series of 3-digit numbers by indicating which digit is different on no-interference (e.g., 003; correct=3) or interference (e.g., 311, correct=3) trials. Performance measures were inverse reaction time (1/RT) and accuracy. A two-way within-subject ANOVA assessed performance across interference and sleep conditions respectively. Results 1/RT showed main-effects of sleep loss (BSLN vs. SR; F(1,148)=4.01;p