0697 IRREGULAR SLEEP SCHEDULE ASSOCIATES WITH DISTURBANCES OF MOOD AND MULTISCALE BEHAVIORAL REGULATION IN COLLEGE STUDENTS

• Published in: Sleep (New York, N.Y.) N.Y.), 2017-04, Vol.40 (suppl_1), p.A258-A258
• Main Authors: To, T, Patxot, M, Li, P, Falvey, B, Lu, C, Yang, H, Lo, M, Scheer, F, Hu, K
• Format: Article
• Language: English
• Subjects: College students; Sleep
• ISSN: 0161-8105; 1550-9109
• DOI: 10.1093/sleepj/zsx050.696

Abstract Introduction: One of the major concerns regarding the lifestyle of college students is irregular sleep-wake cycles that may have adverse health consequences. The goal of this study was to test whether irregular sleep-wake schedules in college students associate with mood decline and perturbed motor activity regulation at multiple time scales. Methods: Forty-four healthy college students (18–30 years old) were studied for 3 weeks during their normal daily routines. Sleep-wake regularity (SWR) was determined based on daily sleep-wake diaries, and depression symptoms were assessed weekly based on the Beck Depression Index (BDI) questionnaire. Motor activity was continuously monitored using a wristband (Actiwatch or LKK ECG-Activity Monitor) throughout the 3 weeks, and data were stored over 1-min bins. To assess motor activity regulation, we calculated interdaily stability (IS) of daily activity rhythms and examined temporal correlations in activity fluctuations during wakefulness at multiple time scales from ~0.1–8 hours. Additionally, mean physical activity levels were assessed weekly based on International Physical Activity Questionnaires. Results: College students with lower SWR had lower IS (p=0.0001) and higher BDI scores (p=0.0003). These associations were independent of physical activity levels. Additionally, for those students with physical activity levels