1120 EFFECTS OF POST-EXPOSURE NAPS ON CHANGE IN AUTONOMIC AROUSAL TO A SOCIAL CHALLENGE ACROSS EXPOSURE THERAPY FOR SOCIAL ANXIETY

• Published in: Sleep (New York, N.Y.) N.Y.), 2017-04, Vol.40 (suppl_1), p.A417-A418
• Main Authors: Kim, S, Bottary, RM, Orr, SP, Hofmann, SG, Simon, NM, Pace-Schott, EF
• Format: Article
• Language: English
• Subjects: Anxiety disorders; Sleep; Social anxiety
• ISSN: 0161-8105; 1550-9109
• DOI: 10.1093/sleepj/zsx050.1119

Abstract Introduction: Sleep promotes memory consolidation and regulates emotion. Sleep may strengthen therapeutic extinction learned during exposure therapy. We investigated effects of post-exposure naps on pre- to post-treatment changes in autonomic arousal during an experimental social stressor in Social Anxiety Disorder. Methods: Twenty-five participants aged 18–36 (16 females) with mean Liebowitz Social Anxiety Scale scores of 85 (96%>60) completed a five-session group exposure therapy for social anxiety. A modified Tier Social Stress Test (mpTSST) was conducted before and after treatment. Heart rate and skin conductance level (SCL) were measured during the baseline, performance (speech and mental math), and recovery periods of the mpTSST. Heart-rate variability measures including root mean square of successive N-to-N intervals (RMSSD) and ratio of low- to high-frequency HR oscillations (sympathovagal balance) were computed. The third and fourth therapy sessions concluded with a speech exposure followed by either a 120-minute nap opportunity (Nap, 14Ss) or a non-arousing video (Wake, 11Ss). Results: The Nap group showed greater pre- to post-treatment decrease in SCL during and while recovering from the social stressor: Time (pre-treatment, post-treatment) x Group (Nap, Wake) interaction [F(1.23)=4.54, p=.044]. The post- compared to pre-treatment SCL during mpTSST decreased in the nap group (p=0.0298) but not the Wake group. There was a trend toward decrease in RMSSD across treatment [F(1.21)=2.96, p=.099] but no group differences. Although the pre-to-post treatment main effect for sympathovagal balance was not significant, a near trend was seen for the Time x Group interaction [F(1.21)=2.57, p=.12], with sympathovagal balance decreasing in the Nap group and slightly increasing in the wake group—the same pattern that was seen for the other sympathetic activity index, SCL. Conclusion: Post-exposure naps promoted faster recovery from a social stressor and also lowered sympathetic activation to the stressor. Sleep augmentation of exposure therapy may show benefit in the treatment of Social Anxiety Disorder Support (If Any): R21MH101567