Design of Hyperthermia Applicator to Heat Multi-Brain Tumors Simultaneously Based on Adaptive Beamforming Technique

Recently, hyperthermia therapy is considered as one of the key treatment principles due to its importance and effectiveness in healing the deep-seated tumors. However, for brain tumors, it is difficult to heat due to high perfusion and thermal conductivity of the head. Therefore, in this research, t...

Full description

Saved in:
Bibliographic Details
Published in:IEEE journal of electromagnetics, RF and microwaves in medicine and biology RF and microwaves in medicine and biology, 2021-06, Vol.5 (2), p.115-123
Main Authors: Mahmoud, Korany R., Montaser, Ahmed M.
Format: Article
Language:English
Subjects:
Antenna array
Antenna arrays
Antennas
Applicators
Beamforming
Brain
Brain cancer
Dielectric properties
Electromagnetic heating
Helmets
Hyperthermia
hyperthermia therapy
Microwave antenna arrays
optimization techniques
Particle swarm optimization
Performance evaluation
Search algorithms
Thermal conductivity
Tumors
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Recently, hyperthermia therapy is considered as one of the key treatment principles due to its importance and effectiveness in healing the deep-seated tumors. However, for brain tumors, it is difficult to heat due to high perfusion and thermal conductivity of the head. Therefore, in this research, the technique of non-invasive heat focalization in multiple tumors, simultaneously, without affecting healthy tissue based on adaptive beamforming was investigated and presented. It is done by controlling the feeding of the antenna array surrounding the brain using a modified hybrid version of gravitational search algorithm and particle swarm optimization (MGSA-PSO). An antenna system in the form of a head helmet was designed and evaluated with 48 antenna elements each of them has a separate excitation that controls the field intensity and beamforming direction towards the tumors. Many scenarios considering a single tumor in different positions with different volumes or multiple tumors are studied to evaluate the performance of the applicator. The helmet was tested on the challenging scenario of a very mature and dense brain with realistic thermal and dielectric properties. The results confirmed the ability of the helmet technology and the proposed antenna system to use a microwave power of 65 W to lift the neoplasm temperature to over 42 °C while keeping healthy tissue safe at 37 degrees with none hot spots. Furthermore, the results showed the capability of the proposed model to treat multiple tumors simultaneously.
ISSN:2469-7249
2469-7257
DOI:10.1109/JERM.2020.3015345