Prodromal Parkinson disease subtypes — key to understanding heterogeneity

In Parkinson disease (PD), pathological processes and neurodegeneration begin long before the cardinal motor symptoms develop and enable clinical diagnosis. In this prodromal phase, risk and prodromal markers can be used to identify individuals who are likely to develop PD, as in the recently update...

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Bibliographic Details
Published in:Nature reviews. Neurology 2021-06, Vol.17 (6), p.349-361
Main Authors: Berg, Daniela, Borghammer, Per, Fereshtehnejad, Seyed-Mohammad, Heinzel, Sebastian, Horsager, Jacob, Schaeffer, Eva, Postuma, Ronald B.
Format: Article
Language:English
Subjects:
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Biomarkers - metabolism
Brain - diagnostic imaging
Brain - metabolism
Development and progression
Diagnosis
Humans
Medicine
Medicine & Public Health
Neuroimaging - methods
Neuroimaging - trends
Neurological research
Neurology
Parkinson Disease - diagnostic imaging
Parkinson Disease - metabolism
Parkinson's disease
Pathology
Phenotype
Prodromal Symptoms
REM sleep
REM Sleep Behavior Disorder - diagnostic imaging
REM Sleep Behavior Disorder - metabolism
Review Article
Risk factors
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