A novel fast-responsive fluorescent probe based on 1,3,5-triazine for endogenous H2S detection with large Stokes shift and its application in cell imaging

A novel fast-responsive fluorescent probe TzAr-H2S was constructed to realize the imaging of endogenous H2S in living cells. This turn-on fluorescent probe TzAr-H2S can quickly (only 20 s) detect H2S with good selectivity, large Stokes shift (100 nm) and low cytotoxicity, which might provide a power...

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Bibliographic Details
Published in:New journal of chemistry 2021-06, Vol.45 (22), p.9756-9760
Main Authors: Zhi-Hao, Zhang, Li, Shaoqing, Yan, Yizhe, Qu, Jianbo, Jian-Yong, Wang
Format: Article
Language:English
Subjects:
Fluorescent indicators
Hydrogen sulfide
Selectivity
Toxicity
Online Access:Get full text
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Summary:A novel fast-responsive fluorescent probe TzAr-H2S was constructed to realize the imaging of endogenous H2S in living cells. This turn-on fluorescent probe TzAr-H2S can quickly (only 20 s) detect H2S with good selectivity, large Stokes shift (100 nm) and low cytotoxicity, which might provide a powerful tool for understanding the regulation mechanism of hydrogen sulfide in cells.
ISSN:1144-0546
1369-9261
DOI:10.1039/d1nj01319j