OBESITY PHENOTYPES AS PREDICTORS OF ARTERIAL HYPERTENSION IN MEN

• Published in: Annals of nutrition and metabolism 2020-01, Vol.76, p.166
• Main Authors: Cardona-Alvarado, M, Nicasio-Flores, M, Figueroa-Vega, N, Paredes-Calderón, C, Pérez-Luque, E
• Format: Article
• Language: English
• Subjects: Adipose tissue; Area; Blood pressure; Body fat; Body mass index; Body size; Correlation analysis; Diabetes; Diabetes mellitus (non-insulin dependent); Dietary supplements; Genotype & phenotype; Glucose; Hip; Hypertension; Lipids; Mens health; Nutrition; Obesity; Phenotypes; Population studies; Risk analysis; Risk factors; Sensitivity; Smoking; Weight
• ISSN: 0250-6807; 1421-9697

Introduction: Abdominal fat (subcutaneous and visceral adipose tissue) is a risk factor for hypertension and type 2 diabetes. There are several anthropometrics measurements detect adiposity phenotypes such as visceral adiposity (BAI) and intra-abdominal fatty area (AGAI). Objective: To evaluate the obesity phenotypes and their association with arterial hypertension in men. Methods: Cross-sectional study in open population. Men aged 30 to 50 years were included, with BMI >18.6kg/m2, clinically healthy or with the presence of hypertension, without changes in weight in the last 6 months (±10%), sedentary, non-smokers, non-alcoholic, without consumption of medications, or nutritional supplements. Weight, height, waist circumference, hip circumference, % body fat, systolic blood pressure (SBP), diastolic (DBP) were measured, and glucose concentrations, and lipid profile were quantified. The following indices were calculated: body mass, waist/hip, waist/height index; BAI= Hip/(Height*1.5)-18); and AGAI= (2.125*age) + (2.843*waist)-225.39. Results: 302 subjects were studied, with an average age of 37 ± 4.6 years and mean body mass index was 30.2 ± 8 kg/m2. The prevalence of hypertension was 23.4%. The correlation analysis shows a positive association of AGAI with the SBP levels (r=0.37, p=0.02), DBP (r=0.30, p=0.01) and glucose (r=0.35, p=0.02). With the waist/height index correlated with SBP levels (r=0.23, p=0.02), DBP (r=0.27, p=0.02) and glucose (r=0.29, p=0.01), positive correlation of glucose levels with the BAI (r=0.30, p=0.03). The area under the curve for the presence of hypertension with the AGAI is 0.73(0.69-0.77), sensitivity of 0.76 and specificity of 0.61, for waist/height index it is 0.69 (0.65-0.73), a sensitivity of 0.70 and specificity of 0.60. Conclusions: The AGAI can be used as a screening test to rule out the presence of hypertension in men aged 30-50 years.