Impact of electrical storm and ablation strategy on 5-year outcome of catheter ablation for ventricular tachycardia in patients with ischaemic and non-ischaemic cardiomyopathies

Introduction: Patients with structural heart disease (SHD) are susceptible to ventricular tachycardia (VT) and arrhythmic death. Use of anti-arrhythmic drugs is often confounded by unacceptable side effects or suboptimal effectiveness. Catheter ablation (CA) is a viable option in these patients. Thi...

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Bibliographic Details
Published in:European journal of arrhythmia & electrophysiology 2021-01, Vol.7, p.25
Main Authors: Man, SH, Ajagu, JO, Chan, N, Somani, R, Stafford, P J, Sandilands, A J, Ibrahim, M, Lazdam, M, Ng, G A, Chin, SH
Format: Article
Language:English
Subjects:
Ablation
Cardiac arrhythmia
Cardiomyopathy
Catheters
Ischemia
Mortality
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Summary:Introduction: Patients with structural heart disease (SHD) are susceptible to ventricular tachycardia (VT) and arrhythmic death. Use of anti-arrhythmic drugs is often confounded by unacceptable side effects or suboptimal effectiveness. Catheter ablation (CA) is a viable option in these patients. This study aims to: 1) determine long-term outcome of patients with SHD undergoing CA for VT; and 2) identify potential predictors of favourable ablation outcome and improved survival. Method: This single-centre longitudinal study enrolled patients with ischaemic (ICM) and non-ischaemic cardiomyopathies (NICM) undergoing CA for VT. Follow-up data on 5-year survival and ICD shocks for VT were collected. Potential demographic, clinical and procedural predictors of VT-free survival were assessed. Cox regression and Kaplan–Meier analyses were performed. Results: Seventy-six patients (ICM 43%, NICM 57%; male 79%) were included. Electrical storm is more prevalent in the ICM group (ICM 50% vs. NICM 14%). At ablation, unstable clinical VT were more prevalent in ICM group (52% vs. 32%, p60 years, LVEF
ISSN:2058-3869
2058-3877