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Synthesis of pyrimido[1,2-a]indoles (minireview)

This review considers methods for the synthesis of pyrimido[1,2- a ]indoles and their ring-fused derivatives, covering publications from the last 10 years. Depending on the synthons used for assembling the target structure, three main approaches to the synthesis of pyrimido-[1,2- a ]indoles can be d...

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Published in:Chemistry of heterocyclic compounds (New York, N.Y. 1965) N.Y. 1965), 2021-10, Vol.57 (10), p.993-995
Main Authors: Nikonov, Igor L., Kopchuk, Dmitry S., Zyryanov, Grigory V., Rusinov, Vladimir L.
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description This review considers methods for the synthesis of pyrimido[1,2- a ]indoles and their ring-fused derivatives, covering publications from the last 10 years. Depending on the synthons used for assembling the target structure, three main approaches to the synthesis of pyrimido-[1,2- a ]indoles can be distinguished: annulation of a pyrimidine ring to 2-aminoindoles, modification of other indole derivatives, and miscellaneous methods.
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subjects Chemical reactions
Chemistry
Chemistry and Materials Science
Indoles
Organic Chemistry
Pharmacy
Pyrimidines
Synthesis
title Synthesis of pyrimido[1,2-a]indoles (minireview)
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