Accuracy of thin-slice model-based iterative reconstruction designed for brain CT to diagnose acute ischemic stroke in the middle cerebral artery territory: a multicenter study

Purpose Model-based iterative reconstruction (MBIR) yields higher spatial resolution and a lower image noise than conventional reconstruction methods. We hypothesized that thin-slice MBIR designed for brain CT could improve the detectability of acute ischemic stroke in the middle cerebral artery (MC...

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Bibliographic Details
Published in:Neuroradiology 2021-12, Vol.63 (12), p.2013-2021
Main Authors: Mitani, Hidenori, Tatsugami, Fuminari, Higaki, Toru, Kaichi, Yoko, Nakamura, Yuko, Smit, Ewoud, Prokop, Mathias, Ono, Chiaki, Ono, Ken, Korogi, Yukunori, Awai, Kazuo
Format: Article
Language:English
Subjects:
Brain
Brain slice preparation
Computed tomography
Diagnostic Neuroradiology
Health care facilities
Image contrast
Image processing
Image reconstruction
Imaging
Infrared imaging
Ischemia
Iterative methods
Lesions
Medical diagnosis
Medical imaging
Medicine
Medicine & Public Health
Model accuracy
Neurology
Neuroradiology
Neurosciences
Neurosurgery
Noise
Radiology
Spatial discrimination
Spatial resolution
Stroke
Territory
Ventricle
Ventricles (cerebral)
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Summary:Purpose Model-based iterative reconstruction (MBIR) yields higher spatial resolution and a lower image noise than conventional reconstruction methods. We hypothesized that thin-slice MBIR designed for brain CT could improve the detectability of acute ischemic stroke in the middle cerebral artery (MCA) territory. Methods Included were 41 patients with acute ischemic stroke in the MCA territory; they were seen at 4 medical centers. The controls were 39 subjects without acute stroke. Images were reconstructed with hybrid IR and with MBIR designed for brain CT at slice thickness of 2 mm. We measured the image noise in the ventricle and compared the contrast-to-noise ratio (CNR) in the ischemic lesion. We analyzed the ability of reconstructed images to detect ischemic lesions using receiver operating characteristics (ROC) analysis; 8 observers read the routine clinical hybrid IR with 5 mm-thick images, while referring to 2 mm-thick hybrid IR images or MBIR images. Results The image noise was significantly lower on MBIR- than hybrid IR images (1.2 vs. 3.4, p  
ISSN:0028-3940
1432-1920
DOI:10.1007/s00234-021-02745-4