Conquering the Hypoxia Limitation for Photodynamic Therapy

Photodynamic therapy (PDT) has aroused great research interest in recent years owing to its high spatiotemporal selectivity, minimal invasiveness, and low systemic toxicity. However, due to the hypoxic nature characteristic of many solid tumors, PDT is frequently limited in therapeutic effect. Moreo...

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Bibliographic Details
Published in:Advanced materials (Weinheim) 2021-12, Vol.33 (48), p.e2103978-n/a
Main Authors: Wan, Yilin, Fu, Lian‐Hua, Li, Chunying, Lin, Jing, Huang, Peng
Format: Article
Language:English
Subjects:
Extracellular Matrix - metabolism
Humans
Hypoxia
Hypoxia-Inducible Factor 1, alpha Subunit - metabolism
Materials science
Nanomaterials
Neoplasms - drug therapy
Normalizing
oxygen
Oxygen - chemistry
Oxygen - metabolism
Oxygen consumption
Oxygen content
Photochemotherapy - methods
Photodynamic therapy
Photosensitizing Agents - chemistry
Photosensitizing Agents - pharmacology
Photosensitizing Agents - therapeutic use
Selectivity
Signal Transduction - drug effects
Toxicity
Tumor Hypoxia - drug effects
Tumor Microenvironment
tumor therapy
Tumors
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