On Reactions of 5-Imino-N,4-diaryl-4,5-dihydro-1,2,4-thiadiazol-3-amines with Phenylethynyl Sulfones

N -Arylthioureas were reacted with hydrogen peroxide to synthesize 5-imino- N ,4-diaryl-4,5-dihydro-1,2,4-thiadiazol-3-amines (Ar = Ph, p -Tol, 4-BrC 6 H 4 ). The products undewent 1,3-dipolar cycloaddition to (R-ethynyl)sulfonyl benzoles (R = Me, Ph, p -Tol, CF 3 ) under mild conditions to form, in...

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Bibliographic Details
Published in:Russian journal of organic chemistry 2022-02, Vol.58 (2), p.219-225
Main Authors: Kostryukov, S. G., Masterova, Yu. Yu, Pugacheva, E. Yu
Format: Article
Language:English
Subjects:
Amines
Chemistry
Chemistry and Materials Science
Cycloaddition
Hydrogen peroxide
Organic Chemistry
Sulfones
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Summary:N -Arylthioureas were reacted with hydrogen peroxide to synthesize 5-imino- N ,4-diaryl-4,5-dihydro-1,2,4-thiadiazol-3-amines (Ar = Ph, p -Tol, 4-BrC 6 H 4 ). The products undewent 1,3-dipolar cycloaddition to (R-ethynyl)sulfonyl benzoles (R = Me, Ph, p -Tol, CF 3 ) under mild conditions to form, in each case, a mixture of the corresponding 5-sulfonyl-substituted N ,4-diarylthiazole-2-amines and N -arylcyanamides.
ISSN:1070-4280
1608-3393
DOI:10.1134/S1070428022020099