Machine Learning-Assisted FTIR Analysis of Circulating Extracellular Vesicles for Cancer Liquid Biopsy

Extracellular vesicles (EVs) are abundantly released into the systemic circulation, where they show remarkable stability and harbor molecular constituents that provide biochemical information about their cells of origin. Due to this characteristic, EVs are attracting increasing attention as a source...

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Bibliographic Details
Published in:Journal of personalized medicine 2022-06, Vol.12 (6), p.949
Main Authors: Di Santo, Riccardo, Vaccaro, Maria, Romanò, Sabrina, Di Giacinto, Flavio, Papi, Massimiliano, Rapaccini, Gian Ludovico, De Spirito, Marco, Miele, Luca, Basile, Umberto, Ciasca, Gabriele
Format: Article
Language:English
Subjects:
Biomarkers
Biopsy
Blood
Classification
Discriminant analysis
Extracellular vesicles
Fourier analysis
Hepatocellular carcinoma
Infrared spectroscopy
Liver cancer
Machine learning
Patients
Precision medicine
Principal components analysis
Software
Spectrum analysis
Statistical analysis
Vitamin K
α-Fetoprotein
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