Salicylic Acid Versus Glycolic Acid Peel in Active Acne

Objective: To compare the efficacies of Salicylic acid and Glycolic acid peel in patients with active acne. Study Design: Quasi-experimental study. Setting and Duration of Study: Department of dermatology, Pak Emirates Military Hospital, (PEMH) Rawalpindi Pakistan, Dec 2018 to Jan 2020. Methodology:...

Full description

Saved in:
Bibliographic Details
Published in:Pakistan Armed Forces medical journal 2022-06, Vol.72 (3), p.896-99
Main Authors: Aftab, Kanza, Iftikhar, Nadia, Hussain, Majid, Zainab, Zarnab, Mumtaz, Maimoona, Obaid, Shanza
Format: Article
Language:English
Subjects:
Acids
Acne
Age
Antiacne agents
Antibiotics
Dermatology
Females
Gender
Hospitals
Phenols
Physicians
Sample size
Skin
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Objective: To compare the efficacies of Salicylic acid and Glycolic acid peel in patients with active acne. Study Design: Quasi-experimental study. Setting and Duration of Study: Department of dermatology, Pak Emirates Military Hospital, (PEMH) Rawalpindi Pakistan, Dec 2018 to Jan 2020. Methodology: A total of 300 patients with active acne were included in this study. Patients were randomized into groups by lottery method. Group-A was given 30% Salicylic acid, while Group-B was given 70% Glycolic acid to control active acne. A grading system developed by Hayashi et al, was used to assess the response. A score less than six after 12 weeks was considered a positive response. In addition, the type of treatment and other factors were compared in the patients with and without a positive response after the designated treatment. Results: Out of 300 patients with active acne included in the study, 172 (57.3%) had a positive response, while 128 (42.7%) had not achieved a positive response after the twelve-week treatment. Use of 30% Salicylic acid, lesser duration of acne and more minor age of the patients had a statistically significant relationship with a positive response in the study population (p-value 0.010, 0.005 and 0.001, respectively). Conclusion: A significant number of patients did not respond to standard therapy of acne vulgaris. However, chances of achieving a positive response increase with 30% Salicylic acid instead of 70% Glycolic acid, lesser duration of acnes and young patients have more chances of getting a positive response at the end of the therapy.
ISSN:0030-9648
2411-8842
DOI:10.51253/pafmj.v72i3.4338