Salicylic Acid Versus Glycolic Acid Peel in Active Acne

Objective: To compare the efficacies of Salicylic acid and Glycolic acid peel in patients with active acne. Study Design: Quasi-experimental study. Setting and Duration of Study: Department of dermatology, Pak Emirates Military Hospital, (PEMH) Rawalpindi Pakistan, Dec 2018 to Jan 2020. Methodology:...

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Published in:Pakistan Armed Forces medical journal 2022-06, Vol.72 (3), p.896-99
Main Authors: Aftab, Kanza, Iftikhar, Nadia, Hussain, Majid, Zainab, Zarnab, Mumtaz, Maimoona, Obaid, Shanza
Format: Article
Language:English
Subjects:
Acids
Acne
Age
Antiacne agents
Antibiotics
Dermatology
Females
Gender
Hospitals
Phenols
Physicians
Sample size
Skin
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container_issue 3
container_start_page 896
container_title Pakistan Armed Forces medical journal
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creator Aftab, Kanza
Iftikhar, Nadia
Hussain, Majid
Zainab, Zarnab
Mumtaz, Maimoona
Obaid, Shanza
description Objective: To compare the efficacies of Salicylic acid and Glycolic acid peel in patients with active acne. Study Design: Quasi-experimental study. Setting and Duration of Study: Department of dermatology, Pak Emirates Military Hospital, (PEMH) Rawalpindi Pakistan, Dec 2018 to Jan 2020. Methodology: A total of 300 patients with active acne were included in this study. Patients were randomized into groups by lottery method. Group-A was given 30% Salicylic acid, while Group-B was given 70% Glycolic acid to control active acne. A grading system developed by Hayashi et al, was used to assess the response. A score less than six after 12 weeks was considered a positive response. In addition, the type of treatment and other factors were compared in the patients with and without a positive response after the designated treatment. Results: Out of 300 patients with active acne included in the study, 172 (57.3%) had a positive response, while 128 (42.7%) had not achieved a positive response after the twelve-week treatment. Use of 30% Salicylic acid, lesser duration of acne and more minor age of the patients had a statistically significant relationship with a positive response in the study population (p-value 0.010, 0.005 and 0.001, respectively). Conclusion: A significant number of patients did not respond to standard therapy of acne vulgaris. However, chances of achieving a positive response increase with 30% Salicylic acid instead of 70% Glycolic acid, lesser duration of acnes and young patients have more chances of getting a positive response at the end of the therapy.
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Study Design: Quasi-experimental study. Setting and Duration of Study: Department of dermatology, Pak Emirates Military Hospital, (PEMH) Rawalpindi Pakistan, Dec 2018 to Jan 2020. Methodology: A total of 300 patients with active acne were included in this study. Patients were randomized into groups by lottery method. Group-A was given 30% Salicylic acid, while Group-B was given 70% Glycolic acid to control active acne. A grading system developed by Hayashi et al, was used to assess the response. A score less than six after 12 weeks was considered a positive response. In addition, the type of treatment and other factors were compared in the patients with and without a positive response after the designated treatment. Results: Out of 300 patients with active acne included in the study, 172 (57.3%) had a positive response, while 128 (42.7%) had not achieved a positive response after the twelve-week treatment. Use of 30% Salicylic acid, lesser duration of acne and more minor age of the patients had a statistically significant relationship with a positive response in the study population (p-value 0.010, 0.005 and 0.001, respectively). Conclusion: A significant number of patients did not respond to standard therapy of acne vulgaris. 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Use of 30% Salicylic acid, lesser duration of acne and more minor age of the patients had a statistically significant relationship with a positive response in the study population (p-value 0.010, 0.005 and 0.001, respectively). Conclusion: A significant number of patients did not respond to standard therapy of acne vulgaris. 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subjects Acids
Acne
Age
Antiacne agents
Antibiotics
Dermatology
Females
Gender
Hospitals
Phenols
Physicians
Sample size
Skin
title Salicylic Acid Versus Glycolic Acid Peel in Active Acne
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